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| NCT ID | NCT06350097 |
| Title | Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer (TROPION-Lung14) |
| Acronym | TROPION-Lung14 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | POL | ITA | FRA | ESP | DEU | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | NOT_YET_RECRUITING | Fountain Valley | California | 92708 | United States | Details |
| Research Site | RECRUITING | Los Alamitos | California | 90720 | United States | Details |
| Research Site | RECRUITING | Los Angeles | California | 90017 | United States | Details |
| Research Site | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| Research Site | WITHDRAWN | Orange | California | 92868 | United States | Details |
| Research Site | RECRUITING | San Diego | California | 92123 | United States | Details |
| Research Site | RECRUITING | Santa Monica | California | 90404 | United States | Details |
| Research Site | RECRUITING | Walnut Creek | California | 94598 | United States | Details |
| Research Site | RECRUITING | New Haven | Connecticut | 06510 | United States | Details |
| Research Site | WITHDRAWN | Washington D.C. | District of Columbia | 20037 | United States | Details |
| Research Site | RECRUITING | Jacksonville | Florida | 32256 | United States | Details |
| Research Site | RECRUITING | Ocala | Florida | 34474 | United States | Details |
| Research Site | RECRUITING | Orange City | Florida | 32763 | United States | Details |
| Research Site | WITHDRAWN | Honolulu | Hawaii | 96819 | United States | Details |
| Research Site | NOT_YET_RECRUITING | North Chicago | Illinois | 60064 | United States | Details |
| Research Site | RECRUITING | Fort Wayne | Indiana | 46845 | United States | Details |
| Research Site | RECRUITING | Bethesda | Maryland | 20817 | United States | Details |
| Research Site | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Research Site | RECRUITING | Saint Paul | Minnesota | 55102 | United States | Details |
| Research Site | WITHDRAWN | Bridgeton | Missouri | 63044 | United States | Details |
| Research Site | RECRUITING | St Louis | Missouri | 63110 | United States | Details |
| Research Site | RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Brooklyn | New York | 11212 | United States | Details |
| Research Site | RECRUITING | New York | New York | 10065 | United States | Details |
| Research Site | WITHDRAWN | Dallas | Texas | 75390 | United States | Details |
| Research Site | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Research Site | WITHDRAWN | Houston | Texas | 77090 | United States | Details |
| Research Site | RECRUITING | Webster | Texas | 77598 | United States | Details |
| Research Site | RECRUITING | Woodway | Texas | 76712 | United States | Details |
| Research Site | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Fort Belvoir | Virginia | 22060 | United States | Details |
| Research Site | RECRUITING | Midlothian | Virginia | 23114 | United States | Details |
| Research Site | WITHDRAWN | Seattle | Washington | 98104 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Camperdown | 2050 | Australia | Details | |
| Research Site | RECRUITING | Clayton | 3168 | Australia | Details | |
| Research Site | RECRUITING | Kogarah | 2217 | Australia | Details | |
| Research Site | RECRUITING | South Brisbane | 4101 | Australia | Details | |
| Research Site | RECRUITING | Westmead | 2145 | Australia | Details | |
| Research Site | RECRUITING | Barretos | 14784-400 | Brazil | Details | |
| Research Site | RECRUITING | Natal | 59075-740 | Brazil | Details | |
| Research Site | RECRUITING | Porto Alegre | 91350-200 | Brazil | Details | |
| Research Site | RECRUITING | Salvador | 41253-190 | Brazil | Details | |
| Research Site | RECRUITING | São Paulo | 01246-000 | Brazil | Details | |
| Research Site | RECRUITING | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H4A 3J1 | Canada | Details |
| Research Site | RECRUITING | Beijing | 100029 | China | Details | |
| Research Site | RECRUITING | Beijing | 100034 | China | Details | |
| Research Site | RECRUITING | Beijing | 100142 | China | Details | |
| Research Site | RECRUITING | Changchun | 130000 | China | Details | |
| Research Site | RECRUITING | Changsha | 410013 | China | Details | |
| Research Site | RECRUITING | Chengdu | 610000 | China | Details | |
| Research Site | RECRUITING | Chengdu | 610042 | China | Details | |
| Research Site | RECRUITING | Chengdu | 610072 | China | Details | |
| Research Site | RECRUITING | Chongqing | 400030 | China | Details | |
| Research Site | RECRUITING | Chongqing | 402260 | China | Details | |
| Research Site | RECRUITING | Guangzhou | 510100 | China | Details | |
| Research Site | RECRUITING | Hangzhou | 310006 | China | Details | |
| Research Site | RECRUITING | Hangzhou | 31000 | China | Details | |
| Research Site | RECRUITING | Hangzhou | 310022 | China | Details | |
| Research Site | RECRUITING | Harbin | 150049 | China | Details | |
| Research Site | RECRUITING | Hefei | 230031 | China | Details | |
| Research Site | RECRUITING | Hefei | 230601 | China | Details | |
| Research Site | RECRUITING | Jinan | 250021 | China | Details | |
| Research Site | RECRUITING | Jinan | 250117 | China | Details | |
| Research Site | RECRUITING | Kunming | 650118 | China | Details | |
| Research Site | RECRUITING | Linhai | 317000 | China | Details | |
| Research Site | RECRUITING | Ningbo | 315010 | China | Details | |
| Research Site | RECRUITING | Shanghai | 200030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Shanghai | 200433 | China | Details | |
| Research Site | RECRUITING | Shenyang | 110004 | China | Details | |
| Research Site | RECRUITING | Wenzhou | 325000 | China | Details | |
| Research Site | RECRUITING | Wuhan | 430022 | China | Details | |
| Research Site | RECRUITING | Wuhan | 430030 | China | Details | |
| Research Site | RECRUITING | Xi'an | 710061 | China | Details | |
| Research Site | RECRUITING | Xuzhou | 221000 | China | Details | |
| Research Site | RECRUITING | Yangzhou | 225001 | China | Details | |
| Research Site | RECRUITING | Zhengzhou | 450000 | China | Details | |
| Research Site | RECRUITING | Zhengzhou | 450008 | China | Details | |
| Research Site | RECRUITING | Angers | 49055 | France | Details | |
| Research Site | RECRUITING | Marseille | 13915 | France | Details | |
| Research Site | RECRUITING | Paris | 75005 | France | Details | |
| Research Site | RECRUITING | Strasbourg | 67091, Cedex | France | Details | |
| Research Site | RECRUITING | Berlin | 13125 | Germany | Details | |
| Research Site | RECRUITING | Cologne | 51109 | Germany | Details | |
| Research Site | RECRUITING | Erfurt | 99089 | Germany | Details | |
| Research Site | RECRUITING | Frankfurt | 60488 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Göttingen | 37075 | Germany | Details | |
| Research Site | RECRUITING | Immenhausen | 34376 | Germany | Details | |
| Research Site | RECRUITING | Kiel | 24105 | Germany | Details | |
| Research Site | RECRUITING | Mainz | 55131 | Germany | Details | |
| Research Site | RECRUITING | München | 81925 | Germany | Details | |
| Research Site | RECRUITING | Hong Kong | 999077 | Hong Kong | Details | |
| Research Site | NOT_YET_RECRUITING | Hong Kong | Hong Kong | Details | ||
| Research Site | RECRUITING | Jordan | HKG | Hong Kong | Details | |
| Research Site | NOT_YET_RECRUITING | Lai Chi Kok | Hong Kong | Details | ||
| Research Site | RECRUITING | Bangalore | 560027 | India | Details | |
| Research Site | SUSPENDED | Delhi | 110085 | India | Details | |
| Research Site | RECRUITING | Hyderabad | 500032 | India | Details | |
| Research Site | SUSPENDED | Kolkata | 700054 | India | Details | |
| Research Site | SUSPENDED | Mysuru | 570017 | India | Details | |
| Research Site | SUSPENDED | Nagpur | 440001 | India | Details | |
| Research Site | RECRUITING | Nashik | 422011 | India | Details | |
| Research Site | SUSPENDED | New Delhi | 100049 | India | Details | |
| Research Site | RECRUITING | New Delhi | 11029 | India | Details | |
| Research Site | RECRUITING | Vadodara | 391760 | India | Details | |
| Research Site | SUSPENDED | Varanasi | 221005 | India | Details | |
| Research Site | RECRUITING | Milan | 20141 | Italy | Details | |
| Research Site | RECRUITING | Monza | 20900 | Italy | Details | |
| Research Site | RECRUITING | Orbassano | 10043 | Italy | Details | |
| Research Site | RECRUITING | Padua | 35128 | Italy | Details | |
| Research Site | RECRUITING | Parma | 43100 | Italy | Details | |
| Research Site | RECRUITING | Chūōku | 104-0045 | Japan | Details | |
| Research Site | RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Research Site | RECRUITING | Kashiwa | 277-8577 | Japan | Details | |
| Research Site | RECRUITING | Kōtoku | 135-8550 | Japan | Details | |
| Research Site | RECRUITING | Niigata | 951-8566 | Japan | Details | |
| Research Site | RECRUITING | Osaka | 541-8567 | Japan | Details | |
| Research Site | RECRUITING | Osakasayama-shi | 589-8511 | Japan | Details | |
| Research Site | RECRUITING | Sapporo | 003-0804 | Japan | Details | |
| Research Site | RECRUITING | Sendai | 981-0914 | Japan | Details | |
| Research Site | RECRUITING | Wakayama | 641-8510 | Japan | Details | |
| Research Site | RECRUITING | Yokohama | 241-8515 | Japan | Details | |
| Research Site | RECRUITING | Bystra | 43-360 | Poland | Details | |
| Research Site | RECRUITING | Olsztyn | 10-357 | Poland | Details | |
| Research Site | RECRUITING | Poznan | 60-569 | Poland | Details | |
| Research Site | RECRUITING | Warsaw | 02-781 | Poland | Details | |
| Research Site | RECRUITING | Rio Piedras | 00935 | Puerto Rico | Details | |
| Research Site | NOT_YET_RECRUITING | San Juan | 00918 | Puerto Rico | Details | |
| Research Site | RECRUITING | Erie | 16544 | South Korea | Details | |
| Research Site | RECRUITING | Goyang-si | 410-769 | South Korea | Details | |
| Research Site | RECRUITING | Namdong-gu | 21565 | South Korea | Details | |
| Research Site | RECRUITING | Seoul | 03080 | South Korea | Details | |
| Research Site | RECRUITING | Seoul | 06351 | South Korea | Details | |
| Research Site | RECRUITING | Seoul | 120-752 | South Korea | Details | |
| Research Site | RECRUITING | A Coruña | 15006 | Spain | Details | |
| Research Site | RECRUITING | Barcelona | 8036 | Spain | Details | |
| Research Site | RECRUITING | Granada | 18007 | Spain | Details | |
| Research Site | RECRUITING | Madrid | 28040 | Spain | Details | |
| Research Site | RECRUITING | Majadahonda | 28222 | Spain | Details | |
| Research Site | RECRUITING | Valencia | 46009 | Spain | Details | |
| Research Site | RECRUITING | Taichung | 40705 | Taiwan | Details | |
| Research Site | RECRUITING | Tainan | 704 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | 106 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | TAIWAN | Taiwan | Details | |
| Research Site | RECRUITING | Taoyuan District | 333 | Taiwan | Details | |
| Research Site | RECRUITING | Bangkok | 10400 | Thailand | Details | |
| Research Site | RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Research Site | RECRUITING | Dusit | 10300 | Thailand | Details | |
| Research Site | RECRUITING | Hat Yai | 90110 | Thailand | Details | |
| Research Site | RECRUITING | Udon Thani | 41000 | Thailand | Details | |
| Research Site | RECRUITING | Adapazarı | 54100 | Turkey (Türkiye) | Details | |
| Research Site | RECRUITING | Ankara | 06530 | Turkey (Türkiye) | Details | |
| Research Site | WITHDRAWN | Goztepe Istanbul | Turkey (Türkiye) | Details | ||
| Research Site | NOT_YET_RECRUITING | Izmir | 35100 | Turkey (Türkiye) | Details | |
| Research Site | RECRUITING | Küçükçekmece | 34295 | Turkey (Türkiye) | Details | |
| Research Site | RECRUITING | Seyhan | 1060 | Turkey (Türkiye) | Details | |
| Research Site | RECRUITING | Hanoi | 100000 | Vietnam | Details | |
| Research Site | RECRUITING | Hà Nội | 100000 | Vietnam | Details | |
| Research Site | RECRUITING | Ho Chi Minh City | 700000 | Vietnam | Details | |
| Research Site | RECRUITING | Ho Chi Minh City | 70000 | Vietnam | Details | |
| Research Site | RECRUITING | Ho Chi Minh City | Vietnam | Details | ||
| Research Site | RECRUITING | Vinh | 460000 | Vietnam | Details |