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| NCT ID | NCT06357533 |
| Title | Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC >= 50%) and Without Actionable Genomic Alterations (TROPION-Lung10) |
| Acronym | TROPION-Lung10 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | ITA | HUN | GBR | ESP | DEU | CAN | BRA | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | NOT_YET_RECRUITING | Anchorage | Alaska | 99508 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Tucson | Arizona | 85719 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Fayetteville | Arkansas | 72703 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Little Rock | Arkansas | 72205 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Beverly Hills | California | 90211 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Glendale | California | 91204 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Long Beach | California | 90806 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Newport Beach | California | 92663 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Gainesville | Florida | 32608 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Miami Beach | Florida | 33140 | United States | Details |
| Research Site | SUSPENDED | Orlando | Florida | 32827 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Punta Gorda | Florida | 33980 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Research Site | WITHDRAWN | Atlanta | Georgia | 30342 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Stockbridge | Georgia | 30281 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Indianapolis | Indiana | 46260 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Annapolis | Maryland | 21401 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Dearborn | Michigan | 48126 | United States | Details |
| Research Site | RECRUITING | Grand Rapids | Michigan | 49503 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Royal Oak | Michigan | 48073 | United States | Details |
| Research Site | WITHDRAWN | Traverse City | Michigan | 49684 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Hattiesburg | Mississippi | 39401 | United States | Details |
| Research Site | WITHDRAWN | Bozeman | Montana | 59715 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Grand Island | Nebraska | 68803 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Omaha | Nebraska | 68130 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Las Vegas | Nevada | 89102 | United States | Details |
| Research Site | SUSPENDED | Reno | Nevada | 89502 | United States | Details |
| Research Site | SUSPENDED | Voorhees | New Jersey | 08043 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Stony Brook | New York | 11794 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Greenville | North Carolina | 27834 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Salisbury | North Carolina | 28144 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Cincinnati | Ohio | 45219 | United States | Details |
| Research Site | WITHDRAWN | Columbus | Ohio | 43210 | United States | Details |
| Research Site | WITHDRAWN | Portland | Oregon | 97213 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Greenville | South Carolina | 29607 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Research Site | WITHDRAWN | Chattanooga | Tennessee | 37404 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Memphis | Tennessee | 38103 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Fort Worth | Texas | 76104 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Houston | Texas | 77030 | United States | Details |
| Research Site | SUSPENDED | Houston | Texas | 77030 | United States | Details |
| Research Site | RECRUITING | Houston | Texas | 77090 | United States | Details |
| Research Site | RECRUITING | Kingwood | Texas | 77339 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Odessa | Texas | 79761 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Fort Belvoir | Virginia | 22060 | United States | Details |
| Research Site | RECRUITING | Leesburg | Virginia | 20176 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Richmond | Virginia | 23230 | United States | Details |
| Research Site | RECRUITING | Tacoma | Washington | 98405 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Vancouver | Washington | 98684 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Wenatchee | Washington | 98801 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Blacktown | 2148 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Clayton | 3168 | Australia | Details | |
| Research Site | RECRUITING | Melbourne | 3000 | Australia | Details | |
| Research Site | RECRUITING | South Brisbane | QL 4101 | Australia | Details | |
| Research Site | WITHDRAWN | Southport | 4215 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Wodonga | 3690 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Innsbruck | 6020 | Austria | Details | |
| Research Site | NOT_YET_RECRUITING | Krems | 3500 | Austria | Details | |
| Research Site | NOT_YET_RECRUITING | Linz | 4020 | Austria | Details | |
| Research Site | NOT_YET_RECRUITING | Rankweil | 6830 | Austria | Details | |
| Research Site | NOT_YET_RECRUITING | Wels | 4600 | Austria | Details | |
| Research Site | NOT_YET_RECRUITING | Wien | 1140 | Austria | Details | |
| Research Site | NOT_YET_RECRUITING | Wien | 1210 | Austria | Details | |
| Research Site | WITHDRAWN | Anderlecht | 1070 | Belgium | Details | |
| Research Site | NOT_YET_RECRUITING | Hasselt | 3500 | Belgium | Details | |
| Research Site | NOT_YET_RECRUITING | La Louvière | 7100 | Belgium | Details | |
| Research Site | NOT_YET_RECRUITING | Liège | 4000 | Belgium | Details | |
| Research Site | RECRUITING | Barretos | 14784-400 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | Curitiba | 80730-150 | Brazil | Details | |
| Research Site | RECRUITING | Florianópolis | 88034-000 | Brazil | Details | |
| Research Site | RECRUITING | Ipatinga | 35162-189 | Brazil | Details | |
| Research Site | RECRUITING | Natal | 59075-740 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | Porto Alegre | 91350-200 | Brazil | Details | |
| Research Site | RECRUITING | Rio de Janeiro | 22211-230 | Brazil | Details | |
| Research Site | RECRUITING | Santa Maria | 97015-450 | Brazil | Details | |
| Research Site | RECRUITING | São Paulo | 01221-020 | Brazil | Details | |
| Research Site | RECRUITING | Taubaté | 12030-200 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | Vancouver | British Columbia | VSZ 4E6 | Canada | Details |
| Research Site | WITHDRAWN | Winnipeg | Manitoba | R3E 0V9 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | St. John's | Newfoundland and Labrador | A1B 3V6 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | London | Ontario | N6A 4L6 | Canada | Details |
| Research Site | WITHDRAWN | Newmarket | Ontario | L3Y 2P9 | Canada | Details |
| Research Site | RECRUITING | Oshawa | Ontario | L1G 2B9 | Canada | Details |
| Research Site | WITHDRAWN | Toronto | Ontario | M4N 3M5 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Lévis | Quebec | G6V 0B8 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H4J 1C5 | Canada | Details |
| Research Site | RECRUITING | Rimouski | Quebec | G5L 5T1 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Trois-Rivieres | Quebec | G8Z 3R9 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details |
| Research Site | RECRUITING | Chicoutimi | G7H 5H6 | Canada | Details | |
| Research Site | NOT_YET_RECRUITING | Beijing | 100142 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Changsha | 410013 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chengdu | 610000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chengdu | 610041 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chongqing | 400030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Fuzhou | 350014 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Guangzhou | 510080 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Nanning | 530021 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Shanghai | 200030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Wuhan | 430000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Wuhan | 430022 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Wuhan | 430030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Bonn | 53113 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Düsseldorf | 40489 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Freiburg | 79106 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Gauting | 82131 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Georgsmarienhütte | 49124 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Gera | 07548 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Gütersloh | 33332 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Hamburg | 20251 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Hamburg | 22087 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Heidelberg | 69126 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Kempten | 87439 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Koblenz | 56068 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Ludwigsburg | 71640 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | München | 81925 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Nürnberg | 90419 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Ravensburg | 88212 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Budapest | 1121 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Gyula | 5700 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Gyöngyös | 3200 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Győr | 9024 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Kecskemét | 6000 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Salgótarján | 3100 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Szekszárd | 7100 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Székesfehérvár | 8000 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Törökbálint | 2045 | Hungary | Details | |
| Research Site | NOT_YET_RECRUITING | Chennai | 600031 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Dwarka | 110075 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Jaipur | 302004 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Kolkata | 700099 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Marg Jaipur | 302004 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Nagpur | 440001 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Nashik | 422011 | India | Details | |
| Research Site | NOT_YET_RECRUITING | New Delhi | 110085 | India | Details | |
| Research Site | NOT_YET_RECRUITING | New Delhi | 11029 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Thiruvananthapuram | 695011 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Bergamo | 24125 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Genoa | 16132 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Milano | 20141 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Milano | 20162 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Monza | 20052 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Padova | 35128 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Pavia | 27100 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Ravenna | 48100 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Roma | 00128 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Rozzano | 20089 | Italy | Details | |
| Research Site | RECRUITING | Fukuoka-shi | 812-8582 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Fukuoka-shi | 814-0180 | Japan | Details | |
| Research Site | RECRUITING | Hidaka-shi | 350-1298 | Japan | Details | |
| Research Site | RECRUITING | Hirosaki-shi | 036-8563 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Hiroshima-shi | 730-8518 | Japan | Details | |
| Research Site | RECRUITING | Kawasaki-shi | 216-8511 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kumamoto-shi | 860-8556 | Japan | Details | |
| Research Site | RECRUITING | Nagoya-shi | 460-0001 | Japan | Details | |
| Research Site | RECRUITING | Okayama | 700-8558 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Osakasayama-shi | 589-8511 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Osaka | 545-8586 | Japan | Details | |
| Research Site | RECRUITING | Sagamihara-shi | 252-0375 | Japan | Details | |
| Research Site | RECRUITING | Sapporo-shi | 003-0804 | Japan | Details | |
| Research Site | RECRUITING | Takaoka-shi | 933-8555 | Japan | Details | |
| Research Site | RECRUITING | Takatsuki-shi | 569-8686 | Japan | Details | |
| Research Site | RECRUITING | Tokushima-shi | 770-8503 | Japan | Details | |
| Research Site | RECRUITING | Tokyo | 104-0045 | Japan | Details | |
| Research Site | RECRUITING | Utsunomiya-shi | 320-0834 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Yokohama-shi | 221-0855 | Japan | Details | |
| Research Site | RECRUITING | Changwon | 51353 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Incheon | 21565 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seongnam-si | 13496 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Suwon-si | 16499 | Korea, Republic of | Details | |
| Research Site | RECRUITING | Suwon | 16247 | Korea, Republic of | Details | |
| Research Site | NOT_YET_RECRUITING | Olsztyn | 10-357 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Poznań | 60-569 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Przemysl | 37-700 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Warszawa | 01-138 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Warszawa | 02-781 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | San Juan | 00935 | Puerto Rico | Details | |
| Research Site | NOT_YET_RECRUITING | Alicante | 03010 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Barcelona | 08003 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Barcelona | 08036 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Jerez de la Frontera | 11407 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Reus,Tarragona | 43204 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Salamanca | 37007 | Spain | Details | |
| Research Site | RECRUITING | Kaohsiung | 80756 | Taiwan | Details | |
| Research Site | RECRUITING | New Taipei | 220 | Taiwan | Details | |
| Research Site | RECRUITING | Taichung | 40447 | Taiwan | Details | |
| Research Site | RECRUITING | Tainan | 704 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | 112 | Taiwan | Details | |
| Research Site | RECRUITING | Taipei | TAIWAN | Taiwan | Details | |
| Research Site | RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Adapazarı | 54100 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Ankara | 06560 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Ankara | 6200 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Antalya | 07070 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Diyarbakir | 21280 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Istanbul | 34030 | Turkey | Details | |
| Research Site | NOT_YET_RECRUITING | Istanbul | 34890 | Turkey | Details | |
| Research Site | RECRUITING | Cheltenham | GL53 7AN | United Kingdom | Details | |
| Research Site | RECRUITING | Inverness | IV2 3UJ | United Kingdom | Details | |
| Research Site | WITHDRAWN | London | SE1 9RT | United Kingdom | Details | |
| Research Site | RECRUITING | London | SW10 9NH | United Kingdom | Details | |
| Research Site | RECRUITING | London | SW17 0QT | United Kingdom | Details | |
| Research Site | NOT_YET_RECRUITING | Preston | PR2 9HT | United Kingdom | Details | |
| Research Site | RECRUITING | Truro | TR1 3LJ | United Kingdom | Details |