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| NCT ID | NCT06435429 |
| Title | A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Jazz Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Arizona Oncology Tucson - Wilmot | RECRUITING | Tucson | Arizona | 85711 | United States | Details |
| University of Arizona Cancer Center | RECRUITING | Tucson | Arizona | 85719 | United States | Details |
| The Oncology Institute Of Hope And Innovation | RECRUITING | Cerritos | California | 90703 | United States | Details |
| USC-Norris Comprehensive Cancer Center - Investigational Drug Service IDS | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| University of Colorado-Cancer Center-PPDS | RECRUITING | Aurora | Colorado | 80045-2517 | United States | Details |
| Rocky Mountain Cancer Centers | RECRUITING | Denver | Colorado | 80218 | United States | Details |
| Medstar Georgetown University Hospital | RECRUITING | Washington | District of Columbia | 20007 | United States | Details |
| Washington Cancer Center | RECRUITING | Washington | District of Columbia | 20010 | United States | Details |
| Florida Cancer Specialists Research South | RECRUITING | Fort Myers | Florida | 33901 | United States | Details |
| Florida Cancer Specialists Research North | RECRUITING | Saint Petersburg | Florida | 33705 | United States | Details |
| Florida Cancer Specialists Research East | RECRUITING | West Palm Beach | Florida | 33401 | United States | Details |
| Dana Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215-5418 | United States | Details |
| Minnesota Oncology Hematology | RECRUITING | Coon Rapids | Minnesota | 55433 | United States | Details |
| Saint Luke's Cancer Institute | RECRUITING | Kansas City | Missouri | 64111 | United States | Details |
| Rutgers Cancer Institute of New Jersey | RECRUITING | New Brunswick | New Jersey | 08901 | United States | Details |
| Perlmutter Cancer Center 160 E 34th St | RECRUITING | New York | New York | 10016-4744 | United States | Details |
| Columbia University Medical Center 161 Fort Washington | RECRUITING | New York | New York | 10032-3729 | United States | Details |
| Messino Cancer Center | RECRUITING | Asheville | North Carolina | 28806 | United States | Details |
| Oncology Hematology Care (OHC) | RECRUITING | Cincinnati | Ohio | 45226 | United States | Details |
| University Hospitals Cleveland Medical Center 11100 Euclid Ave | RECRUITING | Cleveland | Ohio | 44106-1716 | United States | Details |
| Fox Chase Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19111 | United States | Details |
| Sarah Cannon Research Institute | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Texas Oncology - Fort Worth | RECRUITING | Fort Worth | Texas | 76104 | United States | Details |
| Millennium Research and Clinical Development | RECRUITING | Houston | Texas | 77090 | United States | Details |
| Maryland Oncology Hematology Healing Way - USOR | RECRUITING | Irving | Texas | 75063 | United States | Details |
| Medical Oncology Hematology Consultants | RECRUITING | Irving | Texas | 75063 | United States | Details |
| Nexus Health | RECRUITING | Irving | Texas | 75063 | United States | Details |
| Sansum Clinic 540 W - USOR | RECRUITING | Irving | Texas | 75063 | United States | Details |
| Texas Oncology Gulf Coast | RECRUITING | Irving | Texas | 75063 | United States | Details |
| Texas Oncology West | RECRUITING | Irving | Texas | 75063 | United States | Details |
| Virginia Cancer Specialists | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| Virginia Oncology Associates, Sentara Health | RECRUITING | Norfolk | Virginia | 23502 | United States | Details |
| Blue Ridge Cancer Care | RECRUITING | Roanoke | Virginia | 24014 | United States | Details |
| Sunshine Coast University Private Hospital | RECRUITING | Birtinya | Queensland | 4575 | Australia | Details |
| Peninsula and South Eastern Haematology and Oncology Group | RECRUITING | Mount Waverly | Victoria | 3149 | Australia | Details |
| HPS Pharmacies - Adelaide | RECRUITING | Adelaide | 5000 | Australia | Details | |
| The Kinghorn Cancer Centre | RECRUITING | Mt Kuring-gai | 2080 | Australia | Details | |
| St John of God Hospital Subiaco | RECRUITING | Subiaco | 6008 | Australia | Details | |
| Ordensklinikum Barmherzige Schwestern | RECRUITING | Linz | 4010 | Austria | Details | |
| Klinikum Wels-Grieskirchen GmbH - Abteilung für Innere Medizin IV | RECRUITING | Wels | 4600 | Austria | Details | |
| Institute Jules Bordet | RECRUITING | Anderlecht | 1070 | Belgium | Details | |
| UZ Antwerpen | RECRUITING | Edegem | 2650 | Belgium | Details | |
| Grand Hôpital de Charleroi | RECRUITING | Gilly | 6060 | Belgium | Details | |
| CHU UCL Namur - Site Sainte-Elisabeth | RECRUITING | Namur | 5000 | Belgium | Details | |
| AZ Delta- Campus Rumbeke | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| Jewish General Hospital | RECRUITING | Montreal | H3T 1E2 | Canada | Details | |
| The Ottawa Hospital Cancer Centre | RECRUITING | Ottawa | K1H 8L6 | Canada | Details | |
| CHU de Québec Université Laval Hôpital du Saint Sacrement | RECRUITING | Quebec | G1S 4L8 | Canada | Details | |
| BC Cancer-Vancouver Center | RECRUITING | Vancouver | V5Z 4E6 | Canada | Details | |
| Institut Bergonie | RECRUITING | Bordeaux Cedex | 33076 | France | Details | |
| Centre François Baclesse | RECRUITING | Caen | 14000 | France | Details | |
| Centre Georges François Leclerc | RECRUITING | Dijon | 21000 | France | Details | |
| Pharmacie Centre de Cancerologie de la Sarthe | RECRUITING | Le Mans | 72000 | France | Details | |
| Centre Oscar Lambret | RECRUITING | Lille Cedex | 59020 | France | Details | |
| AP HM Hopital de La Timone | RECRUITING | Marseille | 13005 | France | Details | |
| Pharmacie ICM Val d'Aurelle | RECRUITING | Montpellier | 34298 | France | Details | |
| Oncopôle Claudius Regaud Pharmacie | RECRUITING | Toulouse | 31059 | France | Details | |
| Gustave Roussy | RECRUITING | Villejuif | 94800 | France | Details | |
| Helios Klinikum Berlin Buch GmbH Klinik für Gynäkologie und Geburtshilfe | RECRUITING | Berlin | 13125 | Germany | Details | |
| Marienhospital Bottrop gGmbH | RECRUITING | Dortmund | 44263 | Germany | Details | |
| IRCCS Centro di Riferimento Oncologico di Aviano CRO | RECRUITING | Aviano | 33081 | Italy | Details | |
| Asst Papa Giovanni Xxiii | RECRUITING | Bergamo | 24127 | Italy | Details | |
| Azienda Ospedaliero Universitaria Di Bologna Policlinico S Orsola Malpighi Via Massarenti | RECRUITING | Bologna | 40138 | Italy | Details | |
| Ospedale San Raffaele S.r.l PPDS | RECRUITING | Milano | 20132 | Italy | Details | |
| Fondazione IRCCS San Gerardo dei Tintori | RECRUITING | Monza | 20900 | Italy | Details | |
| Istituto Oncologico Veneto - I.R.C.C.S. | RECRUITING | Padova | 35128 | Italy | Details | |
| Fondazione IRCCS Policlinico San Matteo | RECRUITING | Pavia | 27100 | Italy | Details | |
| Chiba Cancer Center | RECRUITING | Chiba-shi | 260-8717 | Japan | Details | |
| National Cancer Center Hospital | RECRUITING | Chuo-ku | 104-0045 | Japan | Details | |
| Osaka International Cancer Institute | RECRUITING | Chuo-Ku | 541-8567 | Japan | Details | |
| Saitama Medical University International Medical Center | RECRUITING | Hidaka-shi | 350-1298 | Japan | Details | |
| Tokai University Hospital | RECRUITING | Isesaki-shi | 259-1193 | Japan | Details | |
| Sagara Hospital | RECRUITING | Kagoshima-Shi | 892-0833 | Japan | Details | |
| Kyoto University Hospital | RECRUITING | Kyoto | 606-8507 | Japan | Details | |
| Aichi Cancer Center | RECRUITING | Nagoya-shi | 464-8681 | Japan | Details | |
| Okayama University Hospital | RECRUITING | Okayama | 700-8558 | Japan | Details | |
| National Hospital Organization Osaka National Hospital | RECRUITING | Osaka-Shi | 540-0006 | Japan | Details | |
| National Hospital Organization Hokkaido Cancer Center | RECRUITING | Sapporo-shi | 003-0804 | Japan | Details | |
| Showa University Hospital | RECRUITING | Tokyo | 142-8666 | Japan | Details | |
| Kanagawa Cancer Center | RECRUITING | Yokohama-shi | 241-8515 | Japan | Details | |
| Soon Chun Hyang University Cheonan Hospital | RECRUITING | Cheonan-si | 330721 | Korea, Republic of | Details | |
| Gachon University Gil Medical Center | RECRUITING | Namdong-gu | 21565 | Korea, Republic of | Details | |
| Gangnam Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | 06273 | Korea, Republic of | Details | |
| The Catholic University of Korea, Seoul St. Mary's Hospital | RECRUITING | Seoul | 137-701 | Korea, Republic of | Details | |
| Severance Hospital Yonsei University Health System | RECRUITING | Seoul | 3722 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 6351 | Korea, Republic of | Details | |
| Pratia MCM Kraków | RECRUITING | Kraków | 30-727 | Poland | Details | |
| Uniwersytecki Szpital Kliniczny w Poznaniu | RECRUITING | Poznan | 60-569 | Poland | Details | |
| Hospital Universitari Vall d Hebron | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Clinic de Barcelona | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Hospital General Universitario de Elche | RECRUITING | Elche | 03203 | Spain | Details | |
| Hospital Universitario Clinico San Cecilio | RECRUITING | Granada | 18016 | Spain | Details | |
| Hospital Beata Maria Ana | RECRUITING | Madrid | 28007 | Spain | Details | |
| MD Anderson Cancer Center | RECRUITING | Madrid | 28033 | Spain | Details | |
| Hospital Clinico San Carlos | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario Fundacion Jimenez Diaz | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario de Canarias | RECRUITING | San Cristóbal de La Laguna | 38320 | Spain | Details | |
| Beatson West Of Scotland Cancer Centre | RECRUITING | Glasgow | G12 0YN | United Kingdom | Details | |
| Guy's Hospital | RECRUITING | London | SE1 9RT | United Kingdom | Details | |
| Charring Cross Hospital | RECRUITING | London | W6 8RF | United Kingdom | Details | |
| The Christie - PPDS | RECRUITING | Manchester | M20 4BX | United Kingdom | Details | |
| New Cross Hospital | RECRUITING | Wolverhampton | WV10 0QP | United Kingdom | Details |