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| NCT ID | NCT06497556 |
| Title | A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer (Krascendo 1) |
| Acronym | Krascendo 1 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | POL | ITA | GBR | FRA | DNK | DEU | BRA | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner Health MD Anderson AZ | RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| Cancer Specialists of North Florida | RECRUITING | Jacksonville | Florida | 32256 | United States | Details |
| New England Cancer Specialists | RECRUITING | Scarborough | Maine | 04074 | United States | Details |
| Nebraska Methodist Estabrook Cancer Center | RECRUITING | Omaha | Nebraska | 68114 | United States | Details |
| Avera Cancer Institute | RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Baptist Clinical Research Institute | RECRUITING | Memphis | Tennessee | 38120 | United States | Details |
| MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Hospital Britanico; Oncologia | RECRUITING | Buenos Aires | C1280AEB | Argentina | Details | |
| Centro Oncologico Korben; Oncology | RECRUITING | Ciudad Autonoma Buenos Aires | C1426AGE | Argentina | Details | |
| Kinghorn Cancer Centre; St Vincents Hospital | RECRUITING | Darlinghurst | New South Wales | 2010 | Australia | Details |
| GenesisCare North Shore | RECRUITING | St Leonards | New South Wales | 2065 | Australia | Details |
| Sunshine Coast University Hospital; The Adem Crosby Centre | RECRUITING | Birtinya | Queensland | 4575 | Australia | Details |
| Lyell McEwin Hospital; Clinical Trials Unit | RECRUITING | Elizabeth Vale | South Australia | 5112 | Australia | Details |
| Peter Maccallum Cancer Centre | RECRUITING | Melbourne | Victoria | 3000 | Australia | Details |
| Hospital Sao Rafael - HSR | RECRUITING | Salvador | BA | 41253-190 | Brazil | Details |
| Hospital Brasilia | RECRUITING | Brasilia | DF | 71635580 | Brazil | Details |
| Oncoclinicas Rio de Janeiro S.A. | RECRUITING | Rio de Janeiro | RJ | 22250-905 | Brazil | Details |
| Santa Casa de Misericordia de Porto Alegre | RECRUITING | Porto Alegre | RS | 90020-090 | Brazil | Details |
| Hospital Nossa Senhora da Conceicao | RECRUITING | Porto Alegre | RS | 90040-373 | Brazil | Details |
| Hospital Mae de Deus | RECRUITING | Porto Alegre | RS | 90110-000 | Brazil | Details |
| Hospital de Cancer de Barretos | RECRUITING | Barretos | SP | 14784-400 | Brazil | Details |
| Hospital de Base de Sao Jose do Rio Preto | RECRUITING | Sao Jose do Rio Preto | SP | 15090-000 | Brazil | Details |
| Hospital Alemao Oswaldo Cruz | RECRUITING | Sao Paulo | SP | 01327-001 | Brazil | Details |
| Aarhus Universitetshospital; Kræftafdelingen | RECRUITING | Aarhus N | 8200 | Denmark | Details | |
| CHU Montpellier | RECRUITING | Montpellier | 34295 | France | Details | |
| CHRU DE STRASBOURG; Département d?Hématologie et Oncologie | RECRUITING | Strasbourg | 67091 | France | Details | |
| Chu Toulouse | RECRUITING | Toulouse | 31059 | France | Details | |
| Universitätsklinikum Essen; Innere Klinik (Tumorforschung) | RECRUITING | Essen | 45147 | Germany | Details | |
| Klinikum Esslingen; Klinik für Kardiologie, Angiologie und Pneumologie | RECRUITING | Esslingen | 73730 | Germany | Details | |
| Krankenhaus Martha-Maria Halle-Doelau gGmbH; Klinik fuer Innere Medizin II | RECRUITING | Halle | 06120 | Germany | Details | |
| Universität Des Saarlandes; Klinik für Innere Medizin V | RECRUITING | Homburg | 66421 | Germany | Details | |
| Lungenfachklinik Immenhausen | RECRUITING | Immenhausen | 34376 | Germany | Details | |
| Universitätsklinikum Münster, Medizinische Klinik A, Translationale Onkologie | RECRUITING | Münster | 48149 | Germany | Details | |
| Universitätsklinikum Regensburg; Klinik und Poliklinik für Innere Medizin II, Pneumologie | RECRUITING | Regensburg | 93053 | Germany | Details | |
| Hong Kong Integrated Oncology Centre | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Queen Mary Hospital; Dept. of Clinical Oncology | RECRUITING | Hong Kong | Hong Kong | Details | ||
| AO Ospedali Riuniti Villa Sofia-Cervello-Presidio Ospedaliero Cervello; Dip. Ematologia e Oncologia | RECRUITING | Palermo | Sicilia | 90146 | Italy | Details |
| Pusan National University Hospital | RECRUITING | Busan | 602-739 | Korea, Republic of | Details | |
| Chungbuk National University Hospital | RECRUITING | Cheongju-si | 28644 | Korea, Republic of | Details | |
| Kyungpook National University Chilgok Hospital | RECRUITING | Daegu | 41404 | Korea, Republic of | Details | |
| Keimyung University Dongsan Medical Center | RECRUITING | Daegu | 41931 | Korea, Republic of | Details | |
| St. Vincent's Hospital | RECRUITING | Gyeonggi-do | 16247 | Korea, Republic of | Details | |
| Pusan National University Yangsan Hospital | RECRUITING | Gyeongsangnam-do | 50612 | Korea, Republic of | Details | |
| Gachon University Gil Medical Center | RECRUITING | Incheon | 21565 | Korea, Republic of | Details | |
| Chonnam National University Hwasun Hospital | RECRUITING | Jeollanam-do | 58128 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | RECRUITING | Seongnam-si | 463-707 | Korea, Republic of | Details | |
| Korea University Anam Hospital | RECRUITING | Seoul | 02841 | Korea, Republic of | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Korea University Guro Hospital | RECRUITING | Seoul | 08308 | Korea, Republic of | Details | |
| Instytut "Centrum Zdrowia Matki Polki"; Klinika Onkologii | RECRUITING | ?ód? | 93-338 | Poland | Details | |
| Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie | RECRUITING | Lublin | 20-954 | Poland | Details | |
| Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie; Oddzial onkologii z pododdzialem chemioterapii | RECRUITING | Olsztyn | 10-357 | Poland | Details | |
| Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu; Oddzial Onkologii Klinicznej | RECRUITING | Poznan | 60-569 | Poland | Details | |
| Radomskie Centrum Onkologii | RECRUITING | Radom | 26-600 | Poland | Details | |
| Instytut Gruzlicy I Chorob Pluc; Iii Klinika Chorob Pluc | RECRUITING | Warszawa | 01-138 | Poland | Details | |
| Gävle Sjukhus; Medicinskt Centrum | RECRUITING | Gävle | 80187 | Sweden | Details | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital | RECRUITING | Kaohsiung City | 807 | Taiwan | Details | |
| Chung Shan Medical University Hospital; Department of Chest | RECRUITING | Taichung | 402306 | Taiwan | Details | |
| National Taiwan University Hospital; Internal Medicince | RECRUITING | Taipei | 00100 | Taiwan | Details | |
| Beatson West of Scotland Cancer Centre | RECRUITING | Glasgow | G12 0YN | United Kingdom | Details | |
| Royal Marsden Hospital - London | RECRUITING | London | SW3 6JJ | United Kingdom | Details |