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NCT ID NCT06564844
Title A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features (TROPION-Lung12)
Acronym TROPION-Lung12
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors AstraZeneca
Indications
lung adenocarcinoma
Therapies
Tegafur-gimeracil-oteracil Potassium
Etoposide
AZD2936 + Datopotamab deruxtecan
Carboplatin
AZD2936
Vinorelbine
Pemetrexed Disodium
Cisplatin
Age Groups: senior | adult
Covered Countries USA | TUR | SWE | POL | NLD | ITA | HUN | GBR | FRA | ESP | DEU | CHE | CAN | BRA | BEL

Facility Status City State Zip Country Details
Research Site NOT_YET_RECRUITING Gilbert Arizona 85234 United States Details
Research Site NOT_YET_RECRUITING Phoenix Arizona 85054 United States Details
Research Site NOT_YET_RECRUITING Tucson Arizona 85710 United States Details
Research Site NOT_YET_RECRUITING Tucson Arizona 85719 United States Details
Research Site NOT_YET_RECRUITING Duarte California 91010 United States Details
Research Site NOT_YET_RECRUITING Fountain Valley California 92708 United States Details
Research Site NOT_YET_RECRUITING Los Angeles California 90033 United States Details
Research Site WITHDRAWN Los Angeles California 90095 United States Details
Research Site NOT_YET_RECRUITING Orange California 92868 United States Details
Research Site NOT_YET_RECRUITING Santa Barbara California 93105 United States Details
Research Site WITHDRAWN Aurora Colorado 80045 United States Details
Research Site NOT_YET_RECRUITING Lone Tree Colorado 80124 United States Details
Research Site WITHDRAWN Newark Delaware 19713 United States Details
Research Site NOT_YET_RECRUITING Fort Myers Florida 33901 United States Details
Research Site NOT_YET_RECRUITING Jacksonville Florida 32224 United States Details
Research Site NOT_YET_RECRUITING Miami Beach Florida 33140 United States Details
Research Site NOT_YET_RECRUITING Miami Florida 33136 United States Details
Research Site WITHDRAWN Orlando Florida 32803 United States Details
Research Site NOT_YET_RECRUITING Saint Petersburg Florida 33709 United States Details
Research Site NOT_YET_RECRUITING West Palm Beach Florida 33401 United States Details
Research Site NOT_YET_RECRUITING Chicago Illinois 60637 United States Details
Research Site NOT_YET_RECRUITING Dyer Indiana 46311 United States Details
Research Site WITHDRAWN Fort Wayne Indiana 46804 United States Details
Research Site NOT_YET_RECRUITING Kansas City Kansas 66160 United States Details
Research Site NOT_YET_RECRUITING Lexington Kentucky 40503 United States Details
Research Site NOT_YET_RECRUITING Annapolis Maryland 21401 United States Details
Research Site NOT_YET_RECRUITING Baltimore Maryland 21201 United States Details
Research Site NOT_YET_RECRUITING Baltimore Maryland 21202 United States Details
Research Site NOT_YET_RECRUITING Boston Massachusetts 02111 United States Details
Research Site WITHDRAWN Boston Massachusetts 02114 United States Details
Research Site NOT_YET_RECRUITING Boston Massachusetts 02115 United States Details
Research Site NOT_YET_RECRUITING Worcester Massachusetts 01655 United States Details
Research Site WITHDRAWN Ann Arbor Michigan 48109 United States Details
Research Site WITHDRAWN Detroit Michigan 48202 United States Details
Research Site NOT_YET_RECRUITING Grand Rapids Michigan 49503 United States Details
Research Site NOT_YET_RECRUITING Royal Oak Michigan 48073 United States Details
Research Site NOT_YET_RECRUITING Troy Michigan 48098 United States Details
Research Site NOT_YET_RECRUITING Duluth Minnesota 55805 United States Details
Research Site NOT_YET_RECRUITING Rochester Minnesota 55905 United States Details
Research Site NOT_YET_RECRUITING Saint Paul Minnesota 55102 United States Details
Research Site NOT_YET_RECRUITING Billings Montana 59102 United States Details
Research Site NOT_YET_RECRUITING Omaha Nebraska 68130 United States Details
Research Site NOT_YET_RECRUITING Las Vegas Nevada 89102 United States Details
Research Site NOT_YET_RECRUITING East Syracuse New York 13057 United States Details
Research Site NOT_YET_RECRUITING Mineola New York 11501 United States Details
Research Site NOT_YET_RECRUITING New York New York 10065 United States Details
Research Site NOT_YET_RECRUITING White Plains New York 10601 United States Details
Research Site NOT_YET_RECRUITING Durham North Carolina 27710 United States Details
Research Site NOT_YET_RECRUITING Cincinnati Ohio 45219 United States Details
Research Site NOT_YET_RECRUITING Cincinnati Ohio 45245 United States Details
Research Site NOT_YET_RECRUITING Cleveland Ohio 44195 United States Details
Research Site WITHDRAWN Portland Oregon 97213 United States Details
Research Site NOT_YET_RECRUITING Portland Oregon 97239 United States Details
Research Site NOT_YET_RECRUITING Allentown Pennsylvania 18104 United States Details
Research Site NOT_YET_RECRUITING Philadelphia Pennsylvania 19107 United States Details
Research Site NOT_YET_RECRUITING Pittsburgh Pennsylvania 15212 United States Details
Research Site WITHDRAWN Pittsburgh Pennsylvania 15213 United States Details
Research Site NOT_YET_RECRUITING Knoxville Tennessee 37920 United States Details
Research Site NOT_YET_RECRUITING Memphis Tennessee 38120 United States Details
Research Site NOT_YET_RECRUITING Nashville Tennessee 37203 United States Details
Research Site NOT_YET_RECRUITING Austin Texas 78745 United States Details
Research Site NOT_YET_RECRUITING Dallas Texas 75204 United States Details
Research Site NOT_YET_RECRUITING Dallas Texas 75231 United States Details
Research Site NOT_YET_RECRUITING Houston Texas 77030 United States Details
Research Site NOT_YET_RECRUITING Houston Texas 77090 United States Details
Research Site NOT_YET_RECRUITING San Antonio Texas 78217 United States Details
Research Site NOT_YET_RECRUITING Webster Texas 77598 United States Details
Research Site NOT_YET_RECRUITING Salt Lake City Utah 84132 United States Details
Research Site NOT_YET_RECRUITING Fairfax Virginia 22031 United States Details
Research Site NOT_YET_RECRUITING Norfolk Virginia 23502 United States Details
Research Site NOT_YET_RECRUITING Seattle Washington 98108 United States Details
Research Site NOT_YET_RECRUITING Seattle Washington 98122 United States Details
Research Site NOT_YET_RECRUITING Edegem 2650 Belgium Details
Research Site NOT_YET_RECRUITING Hasselt 3500 Belgium Details
Research Site NOT_YET_RECRUITING Barretos 14784-057 Brazil Details
Research Site NOT_YET_RECRUITING Brasília 70200-730 Brazil Details
Research Site NOT_YET_RECRUITING Florianópolis 88034-000 Brazil Details
Research Site NOT_YET_RECRUITING Sao Paulo 01323-903 Brazil Details
Research Site NOT_YET_RECRUITING Teresina 64049-200 Brazil Details
Research Site WITHDRAWN St. John's Newfoundland and Labrador A1B 3V6 Canada Details
Research Site RECRUITING Halifax Nova Scotia B3H 2Y9 Canada Details
Research Site WITHDRAWN Newmarket Ontario L3Y 2R2 Canada Details
Research Site NOT_YET_RECRUITING Oshawa Ontario L1G 2B9 Canada Details
Research Site NOT_YET_RECRUITING Greenfield Park Quebec J4V 2H1 Canada Details
Research Site NOT_YET_RECRUITING Montreal Quebec H2X 3J4 Canada Details
Research Site NOT_YET_RECRUITING Angers 49933 France Details
Research Site WITHDRAWN Marseille 13915 France Details
Research Site NOT_YET_RECRUITING Paris Cedex 5 75248 France Details
Research Site NOT_YET_RECRUITING Rouen 76031 France Details
Research Site NOT_YET_RECRUITING Suresnes 92150 France Details
Research Site NOT_YET_RECRUITING Toulon 83000 France Details
Research Site NOT_YET_RECRUITING Bonn 53127 Germany Details
Research Site NOT_YET_RECRUITING Erfurt 99089 Germany Details
Research Site NOT_YET_RECRUITING Essen 45239 Germany Details
Research Site NOT_YET_RECRUITING Esslingen 73730 Germany Details
Research Site NOT_YET_RECRUITING Gauting 82131 Germany Details
Research Site NOT_YET_RECRUITING Georgsmarienhütte 49124 Germany Details
Research Site NOT_YET_RECRUITING Gera 07548 Germany Details
Research Site NOT_YET_RECRUITING Giessen 35392 Germany Details
Research Site NOT_YET_RECRUITING Karlsruhe 76137 Germany Details
Research Site NOT_YET_RECRUITING Kempten 87439 Germany Details
Research Site NOT_YET_RECRUITING Luebeck 23538 Germany Details
Research Site NOT_YET_RECRUITING Münster 48163 Germany Details
Research Site NOT_YET_RECRUITING Würzburg 97067 Germany Details
Research Site NOT_YET_RECRUITING Jordan HKG Hong Kong Details
Research Site NOT_YET_RECRUITING Budapest 1033 Hungary Details
Research Site NOT_YET_RECRUITING Budapest 1083 Hungary Details
Research Site NOT_YET_RECRUITING Budapest 1121 Hungary Details
Research Site NOT_YET_RECRUITING Budapest 1122 Hungary Details
Research Site NOT_YET_RECRUITING Debrecen 4032 Hungary Details
Research Site NOT_YET_RECRUITING Pécs 7624 Hungary Details
Research Site NOT_YET_RECRUITING Törökbálint 2045 Hungary Details
Research Site NOT_YET_RECRUITING Zalaegerszeg 8000 Hungary Details
Research Site NOT_YET_RECRUITING Firenze 50134 Italy Details
Research Site NOT_YET_RECRUITING Monza 20090 Italy Details
Research Site NOT_YET_RECRUITING Padova 35128 Italy Details
Research Site NOT_YET_RECRUITING Roma 00144 Italy Details
Research Site NOT_YET_RECRUITING Roma 00168 Italy Details
Research Site NOT_YET_RECRUITING Rozzano 20089 Italy Details
Research Site NOT_YET_RECRUITING Bunkyo-ku 113-8603 Japan Details
Research Site NOT_YET_RECRUITING Chiba-shi 260-0877 Japan Details
Research Site NOT_YET_RECRUITING Chuo-ku 104-0045 Japan Details
Research Site NOT_YET_RECRUITING Fukuoka-shi 812-8582 Japan Details
Research Site NOT_YET_RECRUITING Hidaka-shi 350-1298 Japan Details
Research Site NOT_YET_RECRUITING Hiroshima-shi 730-8518 Japan Details
Research Site NOT_YET_RECRUITING Hiroshima-shi 734-8551 Japan Details
Research Site NOT_YET_RECRUITING Iwakuni-shi 740-8510 Japan Details
Research Site NOT_YET_RECRUITING Kashiwa 277-8577 Japan Details
Research Site NOT_YET_RECRUITING Kitaadachi-gun 362-0806 Japan Details
Research Site NOT_YET_RECRUITING Kobe-shi 650-0017 Japan Details
Research Site NOT_YET_RECRUITING Koto-ku 135-8550 Japan Details
Research Site NOT_YET_RECRUITING Kumamoto-shi 860-8556 Japan Details
Research Site NOT_YET_RECRUITING Nagoya-shi 464-8681 Japan Details
Research Site NOT_YET_RECRUITING Niigata-shi 951-8566 Japan Details
Research Site NOT_YET_RECRUITING Osakasayama-shi 589-8511 Japan Details
Research Site NOT_YET_RECRUITING Sapporo-shi 003-0804 Japan Details
Research Site NOT_YET_RECRUITING Sendai-shi 980-0873 Japan Details
Research Site NOT_YET_RECRUITING Sendai-shi 980-8574 Japan Details
Research Site NOT_YET_RECRUITING Wakayama-shi 641-8510 Japan Details
Research Site NOT_YET_RECRUITING Yokohama-shi 241-8515 Japan Details
Research Site NOT_YET_RECRUITING Incheon 21565 Korea, Republic of Details
Research Site NOT_YET_RECRUITING Seoul 03722 Korea, Republic of Details
Research Site NOT_YET_RECRUITING Seoul 05505 Korea, Republic of Details
Research Site NOT_YET_RECRUITING Seoul 06351 Korea, Republic of Details
Research Site NOT_YET_RECRUITING Suwon 16247 Korea, Republic of Details
Research Site NOT_YET_RECRUITING George Town 10450 Malaysia Details
Research Site NOT_YET_RECRUITING Kuala Lumpur 50586 Malaysia Details
Research Site NOT_YET_RECRUITING Kuala Lumpur 59100 Malaysia Details
Research Site NOT_YET_RECRUITING Kuching 93586 Malaysia Details
Research Site NOT_YET_RECRUITING Selangor 62250 Malaysia Details
Research Site NOT_YET_RECRUITING Rotterdam 3015 GD Netherlands Details
Research Site NOT_YET_RECRUITING Olsztyn 10-357 Poland Details
Research Site NOT_YET_RECRUITING Warszawa 01-138 Poland Details
Research Site NOT_YET_RECRUITING Alicante 03010 Spain Details
Research Site NOT_YET_RECRUITING Badalona 08003 Spain Details
Research Site NOT_YET_RECRUITING Barcelona 8035 Spain Details
Research Site NOT_YET_RECRUITING Madrid 28040 Spain Details
Research Site NOT_YET_RECRUITING Malaga 29004 Spain Details
Research Site NOT_YET_RECRUITING Zaragoza 50009 Spain Details
Research Site NOT_YET_RECRUITING Solna 171 76 Sweden Details
Research Site NOT_YET_RECRUITING Zurich 8091 Switzerland Details
Research Site NOT_YET_RECRUITING Kaohsiung 80756 Taiwan Details
Research Site NOT_YET_RECRUITING Taipei 10002 Taiwan Details
Research Site NOT_YET_RECRUITING Taipei 112 Taiwan Details
Research Site NOT_YET_RECRUITING Taipei 114 Taiwan Details
Research Site NOT_YET_RECRUITING Taoyuan 333 Taiwan Details
Research Site RECRUITING Bangkoknoi 10700 Thailand Details
Research Site NOT_YET_RECRUITING Bangkok 10400 Thailand Details
Research Site RECRUITING Banphaeo 74120 Thailand Details
Research Site RECRUITING Dusit 10300 Thailand Details
Research Site RECRUITING Hat Yai 90110 Thailand Details
Research Site NOT_YET_RECRUITING Muang 40002 Thailand Details
Research Site RECRUITING Muang 50200 Thailand Details
Research Site NOT_YET_RECRUITING Ratchathewi 10400 Thailand Details
Research Site NOT_YET_RECRUITING Ankara 06010 Turkey Details
Research Site NOT_YET_RECRUITING Ankara 06280 Turkey Details
Research Site NOT_YET_RECRUITING Istanbul 34214 Turkey Details
Research Site NOT_YET_RECRUITING Mersin 33240 Turkey Details
Research Site NOT_YET_RECRUITING Leeds LS9 7TF United Kingdom Details
Research Site NOT_YET_RECRUITING London SE1 9RT United Kingdom Details
Research Site NOT_YET_RECRUITING Nottingham NG5 1PB United Kingdom Details
Research Site NOT_YET_RECRUITING Da Nang 550000 Vietnam Details
Research Site NOT_YET_RECRUITING Ha noi 100000 Vietnam Details
Research Site NOT_YET_RECRUITING Hanoi 100000 Vietnam Details
Research Site NOT_YET_RECRUITING Ho Chi Minh 700000 Vietnam Details
Research Site NOT_YET_RECRUITING Ho Chi Minh 70000 Vietnam Details
Research Site NOT_YET_RECRUITING Vinh 460000 Vietnam Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field