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| NCT ID | NCT06982521 |
| Title | Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer (ReDiscover-2) |
| Acronym | ReDiscover-2 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Relay Therapeutics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | POL | NLD | ITA | GRC | FRA | ESP | DNK | DEU | CZE | CAN | BRA | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner MD Anderson Cancer Center | RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| Beverly Hills Cancer Center | RECRUITING | Beverly Hills | California | 90211 | United States | Details |
| Cedars-Sinai Medical Center | RECRUITING | Beverly Hills | California | 90211 | United States | Details |
| City of Hope | RECRUITING | Duarte | California | 91010 | United States | Details |
| Stanford University School of Medicine | RECRUITING | Palo Alto | California | 94304 | United States | Details |
| University of California Davis | RECRUITING | Sacramento | California | 95817 | United States | Details |
| University of California San Diego | RECRUITING | San Diego | California | 92037 | United States | Details |
| University of California San Francisco | RECRUITING | San Francisco | California | 94143 | United States | Details |
| Kaiser Permanente - Vallejo | RECRUITING | Vallejo | California | 94589 | United States | Details |
| Rocky Mountain Cancer Centers | RECRUITING | Longmont | Colorado | 80504 | United States | Details |
| Yale Cancer Center | RECRUITING | New Haven | Connecticut | 06511 | United States | Details |
| Medical Oncology Hematology Consultants | RECRUITING | Newark | Delaware | 19713 | United States | Details |
| Medstar Georgetown University Hospital | RECRUITING | Washington D.C. | District of Columbia | 20007 | United States | Details |
| Florida Cancer Specialists | RECRUITING | Fort Myers | Florida | 33901 | United States | Details |
| Cancer Care Centers of Brevard | RECRUITING | Palm Bay | Florida | 32909 | United States | Details |
| Rush Medical College | RECRUITING | Chicago | Illinois | 60607 | United States | Details |
| Robert H. Lurie Comprehensive Cancer Center of Northwestern University | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| Community Health Network | RECRUITING | Indianapolis | Indiana | 46250 | United States | Details |
| University of Kansas Medical Center | RECRUITING | Westwood | Kansas | 66205 | United States | Details |
| Cancer Center of Kansas | RECRUITING | Wichita | Kansas | 67214 | United States | Details |
| Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center | RECRUITING | Baltimore | Maryland | 21287 | United States | Details |
| Tufts Medical Center | RECRUITING | Boston | Massachusetts | 02111 | United States | Details |
| Dana Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| University of Michigan Comprehensive Cancer Center | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| Profound Research LLC | RECRUITING | Royal Oak | Michigan | 48073 | United States | Details |
| Minnesota Oncology Hematology | RECRUITING | Minneapolis | Minnesota | 55404 | United States | Details |
| University of Mississippi Medical Center | RECRUITING | Jackson | Mississippi | 39213 | United States | Details |
| Washington University | RECRUITING | St Louis | Missouri | 63110 | United States | Details |
| Nebraska Cancer Specialists | RECRUITING | Omaha | Nebraska | 68130 | United States | Details |
| Renown Regional Medical Center | RECRUITING | Reno | Nevada | 89502 | United States | Details |
| John Theurer Cancer Center at Hackensack University Medical Center | RECRUITING | Hackensack | New Jersey | 07601 | United States | Details |
| Rutgers Cancer Institute | RECRUITING | New Brunswick | New Jersey | 08901 | United States | Details |
| NYU Langone Cancer Center | RECRUITING | New York | New York | 10016 | United States | Details |
| Mount Sinai | RECRUITING | New York | New York | 10029 | United States | Details |
| Columbia University Herbert Irving Medical Center | RECRUITING | New York | New York | 10032 | United States | Details |
| Memorial Sloan-Kettering Cancer Center | RECRUITING | New York | New York | 10065 | United States | Details |
| Oregon Health & Science University | RECRUITING | Portland | Oregon | 97210 | United States | Details |
| Avera Cancer Institute | RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Tennessee Cancer Specialists | RECRUITING | Knoxville | Tennessee | 37909 | United States | Details |
| Tennessee Oncology | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Texas Oncology Central/South | RECRUITING | Austin | Texas | 78745 | United States | Details |
| Texas Oncology DFW | RECRUITING | Dallas | Texas | 75246 | United States | Details |
| UT Southwestern Medical Center | RECRUITING | Dallas | Texas | 75390 | United States | Details |
| Houston Methodist Hospital | RECRUITING | Houston | Texas | 77030 | United States | Details |
| University of Texas M.D. Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Baylor Scott and White Research Institute | RECRUITING | Temple | Texas | 76508 | United States | Details |
| Huntsman Cancer Center, University of Utah | RECRUITING | Salt Lake City | Utah | 84112 | United States | Details |
| Virginia Cancer Specialists | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| Virginia Oncology Associates | RECRUITING | Norfolk | Virginia | 23502 | United States | Details |
| University of Wisconsin | RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| St. Vincent's Hospital Sydney | RECRUITING | Darlinghurst | New South Wales | 2010 | Australia | Details |
| Sydney Adventist Hospital | RECRUITING | Wahroonga | New South Wales | 2076 | Australia | Details |
| Barwon Health | RECRUITING | Geelong | Victoria | 3220 | Australia | Details |
| Peter MacCallum Cancer Center | RECRUITING | Melbourne | Victoria | 3000 | Australia | Details |
| The Alfred Hospital | RECRUITING | Melbourne | Victoria | 3004 | Australia | Details |
| Sunshine Hospital | RECRUITING | Saint Albans | Victoria | 3021 | Australia | Details |
| Ballarat Oncology & Haematology Service | RECRUITING | Wendouree | Victoria | 3355 | Australia | Details |
| Medical University of Graz | RECRUITING | Graz | 8010 | Austria | Details | |
| Ordensklinikum Linz GmbH | RECRUITING | Linz | 4010 | Austria | Details | |
| LKH Feldkirch, Interne E am LKH Rankweil | RECRUITING | Rankweil | 6830 | Austria | Details | |
| Centre Hospitalier de l'Ardenne | RECRUITING | Libramont | 6800 | Belgium | Details | |
| CHU-UCL Namur, Site Sainte-Elisabeth | RECRUITING | Namur | Belgium | Details | ||
| Vitaz, Campus Sint-Niklaas | RECRUITING | Sint-Niklaas | Belgium | Details | ||
| CHR de Verviers site Tourelle | RECRUITING | Verviers | 4800 | Belgium | Details | |
| CEON+ Pesquisas | RECRUITING | São Caetano do Sul | São Paulo | 09541-270 | Brazil | Details |
| Centro de Pesquisa Oncoclinica Natal Oncoclinicas | RECRUITING | Natal | 59020-505 | Brazil | Details | |
| Irmandade da Santa Casa de Misericórdia de Porto Alegre | RECRUITING | Porto Alegre | 90020-090 | Brazil | Details | |
| Centro Gaúcho Integrado de Oncologia, Hematologia, Ensino e Pesquisa | RECRUITING | Porto Alegre | 90110-270 | Brazil | Details | |
| Centro de Pesquisa Clínica da Associação Hospitalar Moinhos de Vento | RECRUITING | Porto Alegre | 90560-032 | Brazil | Details | |
| Centro de Pesquisa em Oncologia - PUCRS | RECRUITING | Porto Alegre | 90610-000 | Brazil | Details | |
| Oncoclinicas Rio de Janeiro | RECRUITING | Rio de Janeiro | 22250-905 | Brazil | Details | |
| Instituto de Educação Pesquisa e Gestão em Saúde | RECRUITING | Rio de Janeiro | 22775-001 | Brazil | Details | |
| NOB (Nucleo de Oncologia da Bahia) | RECRUITING | Salvador | 40170-110 | Brazil | Details | |
| William Osler Health System- Brampton Civic Hospital | RECRUITING | Brampton | Ontario | L6R 3J7 | Canada | Details |
| Ottawa Hospital Research Institute | RECRUITING | Ottawa | Ontario | K1H8L6 | Canada | Details |
| Sunnybrook Research Institute | RECRUITING | Toronto | Ontario | M4N 3M5 | Canada | Details |
| Jewish General Hospital | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Masarykuv onkologicky ustav | RECRUITING | Brno | 656 33 | Czechia | Details | |
| Aalborg University Hospital | RECRUITING | Aalborg | Denmark | Details | ||
| Zealand University Hospital | RECRUITING | Næstved | 4700 | Denmark | Details | |
| Sygehus Sønderjylland | RECRUITING | Sønderborg | Denmark | Details | ||
| Centre Leon Berard | RECRUITING | Lyon | 69008 | France | Details | |
| Marienhospital Bottrop gGmbH | RECRUITING | Bottrop | 46236 | Germany | Details | |
| Studienzentrale für das MVZ Eggenfelden GbR | RECRUITING | Eggenfelden | 84307 | Germany | Details | |
| Praxis fuer Interdisziplinaere Onkologie und Haematologie | RECRUITING | Freiburg im Breisgau | 79110 | Germany | Details | |
| Iaso Hospital | RECRUITING | Athens | 151 21 | Greece | Details | |
| Interbalkan Hospital of Thessaloniki | RECRUITING | Thessaloniki | 570 01 | Greece | Details | |
| Hong Kong United Oncology Centre | RECRUITING | Hong Kong | HGK | Hong Kong | Details | |
| Queen Mary Hospital | RECRUITING | Hong Kong | HGK | Hong Kong | Details | |
| IRCCS Candiolo | RECRUITING | Candiolo | 10060 | Italy | Details | |
| AOU Ferrara, Arcispedale Sant'Anna | RECRUITING | Cona | 44124 | Italy | Details | |
| Azienda Ospedaliera Universitaria Careggi | RECRUITING | Florence | 50134 | Italy | Details | |
| Maastricht University Medical Center | RECRUITING | Maastricht | 6229 | Netherlands | Details | |
| Radboud UMC | RECRUITING | Nijmegen | 6525 | Netherlands | Details | |
| Haga Ziekenhuis | RECRUITING | The Hague | 2545 | Netherlands | Details | |
| Pratia MCM Krakow | RECRUITING | Krakow | 30-727 | Poland | Details | |
| Curie Oncology | RECRUITING | Singapore | 217562 | Singapore | Details | |
| CHA Bundang Medical Center, CHA University | RECRUITING | Seongnam-si | 13496 | South Korea | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | South Korea | Details | |
| Gangnam Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | 06273 | South Korea | Details | |
| Samsung Medical Center | RECRUITING | Seoul | 06351 | South Korea | Details | |
| The Catholic University, Seoul St. Mary's Hospital | RECRUITING | Seoul | 06591 | South Korea | Details | |
| Korea University Guro Hospital | RECRUITING | Seoul | 08308 | South Korea | Details | |
| Seoul National University Bundang Hospital | RECRUITING | Seoul | 13620 | South Korea | Details | |
| Hospital Universitario de Badajoz | RECRUITING | Badajoz | 06006 | Spain | Details | |
| Hospital Universitari Vall d'Hebron | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Clinic de Barcelona | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Hospital San Pedro de Alcantara | RECRUITING | Cáceres | 10003 | Spain | Details | |
| Hospital Universitario Juan Ramon Jimenez | RECRUITING | Huelva | 21005 | Spain | Details | |
| Hospital Universitari Arnau de Vilanova | RECRUITING | Lleida | 25198 | Spain | Details | |
| Hospital Beata Maria Ana/IOB Madrid | RECRUITING | Madrid | 28007 | Spain | Details | |
| Clinica Universidad de Navarra | RECRUITING | Madrid | 28027 | Spain | Details | |
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | 28041 | Spain | Details | |
| Hospital General Universitario Morales Meseguer | RECRUITING | Murcia | 30008 | Spain | Details | |
| Hospital Universitario de Canarias | RECRUITING | San Cristóbal de La Laguna | 38320 | Spain | Details | |
| Kaohsiung Chang Gung Memorial Hospital | RECRUITING | Kaohsiung City | 833 | Taiwan | Details | |
| Taichung Veterans General Hospital | RECRUITING | Taichung | 407219 | Taiwan | Details | |
| National Taiwan University Hospital | RECRUITING | Taipei | 100225 | Taiwan | Details | |
| Taipei Veterans General Hospital | RECRUITING | Taipei | 11217 | Taiwan | Details | |
| Chang Gung Memorial Hospital, Linkou | RECRUITING | Taoyuan | 333 | Taiwan | Details |