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| NCT ID | NCT07100080 |
| Title | Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01) |
| Acronym | IZABRIGHT-Lung01 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Bristol-Myers Squibb |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ROU | POL | NOR | NLD | ITA | GRC | GBR | FRA | ESP | DEU | CHE | CAN | BEL | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Local Institution - 0279 | NOT_YET_RECRUITING | Irvine | California | 92612 | United States | Details |
| Local Institution - 0154 | NOT_YET_RECRUITING | Orange | California | 92868 | United States | Details |
| Shaw Cancer Center | RECRUITING | Edwards | Colorado | 81632 | United States | Details |
| Local Institution - 0085 | WITHDRAWN | Gainesville | Florida | 32610 | United States | Details |
| Local Institution - 0142 | NOT_YET_RECRUITING | Pembroke Pines | Florida | 33028 | United States | Details |
| Local Institution - 0270 | NOT_YET_RECRUITING | Atlanta | Georgia | 30318 | United States | Details |
| Local Institution - 0143 | NOT_YET_RECRUITING | Columbus | Georgia | 31904 | United States | Details |
| Local Institution - 0153 | NOT_YET_RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Washington University School of Medicine | RECRUITING | St Louis | Missouri | 63108 | United States | Details |
| Renown Regional Medical Center | RECRUITING | Reno | Nevada | 89502 | United States | Details |
| Perlmutter Cancer Center at NYU Langone Hospital - Long Island | RECRUITING | Mineola | New York | 11501 | United States | Details |
| NYU Langone Health | RECRUITING | New York | New York | 10016 | United States | Details |
| Local Institution - 0158 | NOT_YET_RECRUITING | New York | New York | 10065 | United States | Details |
| Local Institution - 0186 | NOT_YET_RECRUITING | Rochester | New York | 14621 | United States | Details |
| University Hospitals Cleveland Medical Center | RECRUITING | Cleveland | Ohio | 44106 | United States | Details |
| Local Institution - 0284 | NOT_YET_RECRUITING | Columbus | Ohio | 43210 | United States | Details |
| Local Institution - 0038 | NOT_YET_RECRUITING | Portland | Oregon | 97213 | United States | Details |
| Local Institution - 0275 | NOT_YET_RECRUITING | Portland | Oregon | 97225 | United States | Details |
| Local Institution - 0171 | NOT_YET_RECRUITING | Portland | Oregon | 97239 | United States | Details |
| Hospital of the University of Pennsylvania | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Local Institution - 0088 | NOT_YET_RECRUITING | Pittsburgh | Pennsylvania | 15212 | United States | Details |
| Local Institution - 0268 | WITHDRAWN | Chattanooga | Tennessee | 37404 | United States | Details |
| Tennessee Oncology | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Local Institution - 0025 | NOT_YET_RECRUITING | Houston | Texas | 77030 | United States | Details |
| Local Institution - 0173 | NOT_YET_RECRUITING | San Antonio | Texas | 78229 | United States | Details |
| University of Virginia Health System | RECRUITING | Charlottesville | Virginia | 22908 | United States | Details |
| Local Institution - 0138 | NOT_YET_RECRUITING | Richmond | Virginia | 23219 | United States | Details |
| Local Institution - 0008 | NOT_YET_RECRUITING | Ciudad Autónoma de Buenos Aires | Buenos Aires | C1426ANZ | Argentina | Details |
| Local Institution - 0004 | NOT_YET_RECRUITING | ABB | Buenos Aires F.D. | C1199ABB | Argentina | Details |
| Local Institution - 0094 | NOT_YET_RECRUITING | Córdoba | Córdoba Province | 5016 | Argentina | Details |
| Local Institution - 0280 | NOT_YET_RECRUITING | Wilrijk | Antwerpen | 2610 | Belgium | Details |
| Local Institution - 0161 | NOT_YET_RECRUITING | Auderghem | Bruxelles-Capitale, Région de | 1160 | Belgium | Details |
| Local Institution - 0022 | NOT_YET_RECRUITING | Yvoir | Namur | 5530 | Belgium | Details |
| Local Institution - 0023 | NOT_YET_RECRUITING | Ghent | Oost-Vlaanderen | 9000 | Belgium | Details |
| Local Institution - 0024 | NOT_YET_RECRUITING | Sint-Niklaas | Oost-Vlaanderen | B-9100 | Belgium | Details |
| Local Institution - 0190 | NOT_YET_RECRUITING | Calgary | Alberta | T2N 5G2 | Canada | Details |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Local Institution - 0184 | NOT_YET_RECRUITING | Chicoutimi | Quebec | G7H 5H6 | Canada | Details |
| Local Institution - 0185 | NOT_YET_RECRUITING | Montreal | Quebec | H4J 1C5 | Canada | Details |
| Local Institution - 0006 | NOT_YET_RECRUITING | Santiago | Santiago Metropolitan | 0 | Chile | Details |
| Local Institution - 0005 | NOT_YET_RECRUITING | Santiago | Santiago Metropolitan | 7500921 | Chile | Details |
| Local Institution - 0007 | NOT_YET_RECRUITING | Santiago | Santiago Metropolitan | 8420383 | Chile | Details |
| Local Institution - 0244 | NOT_YET_RECRUITING | Beijing | Beijing Municipality | 100142 | China | Details |
| Local Institution - 0259 | NOT_YET_RECRUITING | Chongqing | Chongqing Municipality | 400030 | China | Details |
| Local Institution - 0253 | NOT_YET_RECRUITING | Fuzhou | Fujian | 350014 | China | Details |
| Jiangmen Center Hospital | RECRUITING | Jiangmen | Guangdong | 0 | China | Details |
| Local Institution - 0271 | NOT_YET_RECRUITING | Anyang | Henan | 455000 | China | Details |
| Local Institution - 0261 | NOT_YET_RECRUITING | Luoyang | Henan | 471003 | China | Details |
| Local Institution - 0267 | NOT_YET_RECRUITING | Jingzhou | Hubei | 0 | China | Details |
| Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology | RECRUITING | Wuhan | Hubei | 430030 | China | Details |
| Local Institution - 0255 | NOT_YET_RECRUITING | Changsha | Hunan | 410013 | China | Details |
| Local Institution - 0256 | NOT_YET_RECRUITING | Xuzhou | Jiangsu | 221009 | China | Details |
| Local Institution - 0247 | NOT_YET_RECRUITING | Nanchang | Jiangxi | 330209 | China | Details |
| Local Institution - 0246 | NOT_YET_RECRUITING | Changchun | Jilin | 130000 | China | Details |
| Local Institution - 0257 | NOT_YET_RECRUITING | Shenyang | Liaoning | 110001 | China | Details |
| Local Institution - 0248 | NOT_YET_RECRUITING | Jinan | Shandong | 250117 | China | Details |
| Local Institution - 0250 | NOT_YET_RECRUITING | Shanghai | Shanghai Municipality | 200030 | China | Details |
| Local Institution - 0258 | NOT_YET_RECRUITING | Taiyuan | Shanxi | 030000 | China | Details |
| Local Institution - 0252 | NOT_YET_RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Local Institution - 0251 | NOT_YET_RECRUITING | Linhai | Zhejiang | 317000 | China | Details |
| Local Institution - 0260 | NOT_YET_RECRUITING | Nanning | 530021 | China | Details | |
| Local Institution - 0249 | NOT_YET_RECRUITING | Shanghai | 200032 | China | Details | |
| Local Institution - 0229 | NOT_YET_RECRUITING | Valledupar | Cesar Department | 200001 | Colombia | Details |
| Local Institution - 0228 | NOT_YET_RECRUITING | Bogotá | Cundinamarca | 111511 | Colombia | Details |
| Local Institution - 0227 | NOT_YET_RECRUITING | Montería | Departamento de Córdoba | 230002 | Colombia | Details |
| Local Institution - 0226 | NOT_YET_RECRUITING | Cali | Valle del Cauca Department | 760032 | Colombia | Details |
| Local Institution - 0014 | NOT_YET_RECRUITING | Strasbourg | Alsace | 67091 | France | Details |
| Local Institution - 0017 | NOT_YET_RECRUITING | Toulouse | Haute-Garonne | 31059 | France | Details |
| Local Institution - 0010 | NOT_YET_RECRUITING | Lille | Hauts-de-France | 59037 | France | Details |
| Local Institution - 0018 | NOT_YET_RECRUITING | La Tronche | Isère | 38700 | France | Details |
| Local Institution - 0170 | NOT_YET_RECRUITING | Saint-Herblain | Loire-Atlantique | 44805 | France | Details |
| Local Institution - 0162 | NOT_YET_RECRUITING | Bron | Rhône | 69677 | France | Details |
| Local Institution - 0019 | NOT_YET_RECRUITING | Villejuif | Val-de-Marne | 94800 | France | Details |
| Local Institution - 0012 | NOT_YET_RECRUITING | Marseille | 13915 | France | Details | |
| Local Institution - 0278 | NOT_YET_RECRUITING | Nantes | 44200 | France | Details | |
| Local Institution - 0011 | NOT_YET_RECRUITING | Paris | 75248 | France | Details | |
| Local Institution - 0015 | NOT_YET_RECRUITING | Paris | 75970 | France | Details | |
| Local Institution - 0207 | NOT_YET_RECRUITING | Esslingen am Neckar | Baden-Wurttemberg | 73730 | Germany | Details |
| Local Institution - 0238 | NOT_YET_RECRUITING | Esslingen am Neckar | Baden-Wurttemberg | 73730 | Germany | Details |
| Local Institution - 0212 | NOT_YET_RECRUITING | Stuttgart | Baden-Wurttemberg | 70376 | Germany | Details |
| Local Institution - 0236 | NOT_YET_RECRUITING | Donauwörth | Bavaria | 86609 | Germany | Details |
| Local Institution - 0209 | NOT_YET_RECRUITING | Oldenburg | Lower Saxony | 26121 | Germany | Details |
| Local Institution - 0213 | NOT_YET_RECRUITING | Cologne | North Rhine-Westphalia | 51109 | Germany | Details |
| Local Institution - 0208 | NOT_YET_RECRUITING | Chemnitz | Saxony | 09116 | Germany | Details |
| Local Institution - 0274 | NOT_YET_RECRUITING | Kiel | Schleswig-Holstein | 24105 | Germany | Details |
| Local Institution - 0211 | NOT_YET_RECRUITING | Berlin | 13125 | Germany | Details | |
| Local Institution - 0215 | NOT_YET_RECRUITING | Gauting | 82131 | Germany | Details | |
| Local Institution - 0242 | NOT_YET_RECRUITING | Hamburg | 22307 | Germany | Details | |
| Local Institution - 0210 | NOT_YET_RECRUITING | Heidelberg | 69126 | Germany | Details | |
| Local Institution - 0239 | NOT_YET_RECRUITING | Kassel | 34125 | Germany | Details | |
| Local Institution - 0241 | NOT_YET_RECRUITING | Ulm | 89081 | Germany | Details | |
| Local Institution - 0054 | NOT_YET_RECRUITING | Athens | Attikí | 115 27 | Greece | Details |
| Local Institution - 0060 | NOT_YET_RECRUITING | Chaïdári | Attikí | 124 62 | Greece | Details |
| Local Institution - 0056 | NOT_YET_RECRUITING | Thessaloniki | Kentrikí Makedonía | 540 07 | Greece | Details |
| Local Institution - 0062 | NOT_YET_RECRUITING | Thessaloniki | Thessaloníki | 570 10 | Greece | Details |
| Local Institution - 0083 | WITHDRAWN | Ahmedabad | Gujarat | 380016 | India | Details |
| Local Institution - 0073 | NOT_YET_RECRUITING | Ahmedabad | Gujarat | 380054 | India | Details |
| Local Institution - 0072 | WITHDRAWN | Gurugram | Haryana | 122001 | India | Details |
| Local Institution - 0069 | NOT_YET_RECRUITING | Bengaluru | Karnataka | 560017 | India | Details |
| Local Institution - 0077 | NOT_YET_RECRUITING | Mumbai | Maharashtra | 400 057 | India | Details |
| Local Institution - 0071 | NOT_YET_RECRUITING | Mumbai | Maharashtra | 400012 | India | Details |
| Local Institution - 0097 | NOT_YET_RECRUITING | Nagpur | Maharashtra | 440001 | India | Details |
| Local Institution - 0070 | NOT_YET_RECRUITING | New Delhi | National Capital Territory of Delhi | 110029 | India | Details |
| Local Institution - 0078 | WITHDRAWN | Howrah | West Bengal | 711103 | India | Details |
| Local Institution - 0028 | NOT_YET_RECRUITING | Ravenna | Emilia-Romagna | 48121 | Italy | Details |
| Local Institution - 0036 | NOT_YET_RECRUITING | Aviano | Friuli Venezia Giulia | 33081 | Italy | Details |
| Local Institution - 0031 | NOT_YET_RECRUITING | Orbassano | Piedmont | 10043 | Italy | Details |
| Local Institution - 0277 | NOT_YET_RECRUITING | Candiolo | Torino | 10060 | Italy | Details |
| Local Institution - 0137 | NOT_YET_RECRUITING | Avellino | 83100 | Italy | Details | |
| Local Institution - 0032 | NOT_YET_RECRUITING | Milan | 20141 | Italy | Details | |
| Local Institution - 0034 | NOT_YET_RECRUITING | Naples | 80131 | Italy | Details | |
| Local Institution - 0029 | NOT_YET_RECRUITING | Parma | 43126 | Italy | Details | |
| Local Institution - 0196 | NOT_YET_RECRUITING | Nagoya | Aichi-ken | 464-8681 | Japan | Details |
| Local Institution - 0191 | NOT_YET_RECRUITING | Kashiwa | Chiba | 277-8577 | Japan | Details |
| Local Institution - 0203 | NOT_YET_RECRUITING | Tōon | Ehime | 791-0295 | Japan | Details |
| Local Institution - 0201 | NOT_YET_RECRUITING | Kurume | Fukuoka | 830-0011 | Japan | Details |
| Local Institution - 0217 | NOT_YET_RECRUITING | Sapporo | Hokkaido | 003-0804 | Japan | Details |
| Local Institution - 0199 | NOT_YET_RECRUITING | Nishinomiya | Hyōgo | 663-8501 | Japan | Details |
| Local Institution - 0193 | NOT_YET_RECRUITING | Yokohama | Kanagawa | 2418515 | Japan | Details |
| Local Institution - 0192 | NOT_YET_RECRUITING | Sendai | Miyagi | 9810914 | Japan | Details |
| Local Institution - 0200 | NOT_YET_RECRUITING | Kurashiki | Okayama-ken | 710-8602 | Japan | Details |
| Local Institution - 0198 | NOT_YET_RECRUITING | Hirakata | Osaka | 573-1191 | Japan | Details |
| Local Institution - 0204 | NOT_YET_RECRUITING | Ōsaka-sayama | Osaka | 589-8511 | Japan | Details |
| Local Institution - 0194 | WITHDRAWN | Ina-machi | Saitama | 362-0806 | Japan | Details |
| Local Institution - 0197 | NOT_YET_RECRUITING | Hamamatsu | Shizuoka | 431-3192 | Japan | Details |
| Local Institution - 0195 | NOT_YET_RECRUITING | Nagaizumi-cho,Sunto-gun | Shizuoka | 411-8777 | Japan | Details |
| Local Institution - 0202 | NOT_YET_RECRUITING | Koto-ku | Tokyo | 135-8550 | Japan | Details |
| Local Institution - 0225 | NOT_YET_RECRUITING | Mexico City | Mexico City | 03100 | Mexico | Details |
| Local Institution - 0224 | NOT_YET_RECRUITING | Oaxaca City | Oaxaca | 68020 | Mexico | Details |
| Local Institution - 0222 | NOT_YET_RECRUITING | Chihuahua City | 31203 | Mexico | Details | |
| Local Institution - 0223 | NOT_YET_RECRUITING | Mexico City | 14210 | Mexico | Details | |
| Local Institution - 0163 | NOT_YET_RECRUITING | Harderwijk | Gelderland | 3844 DG | Netherlands | Details |
| Local Institution - 0216 | NOT_YET_RECRUITING | Amsterdam | North Holland | 1066 CX | Netherlands | Details |
| Local Institution - 0164 | NOT_YET_RECRUITING | Amsterdam | North Holland | 1081 HV | Netherlands | Details |
| Local Institution - 0103 | NOT_YET_RECRUITING | Drammen | Buskerud | 3004 | Norway | Details |
| Local Institution - 0106 | NOT_YET_RECRUITING | Bergen | Hordaland | 5021 | Norway | Details |
| Local Institution - 0105 | NOT_YET_RECRUITING | Oslo | 0450 | Norway | Details | |
| Local Institution - 0220 | NOT_YET_RECRUITING | Lublin | Lublin Voivodeship | 20-954 | Poland | Details |
| Local Institution - 0231 | NOT_YET_RECRUITING | Gdynia | Pomeranian Voivodeship | 81-519 | Poland | Details |
| Local Institution - 0219 | NOT_YET_RECRUITING | Bydgoszcz | 85796 | Poland | Details | |
| Local Institution - 0120 | NOT_YET_RECRUITING | Bucharest | București | 013812 | Romania | Details |
| Local Institution - 0123 | NOT_YET_RECRUITING | Bucharest | București | 022328 | Romania | Details |
| Local Institution - 0132 | NOT_YET_RECRUITING | Florești | Cluj | 407280 | Romania | Details |
| Local Institution - 0130 | NOT_YET_RECRUITING | Craiova | Dolj | 200746 | Romania | Details |
| Local Institution - 0115 | NOT_YET_RECRUITING | Bucharest | 020335 | Romania | Details | |
| Local Institution - 0133 | NOT_YET_RECRUITING | Cluj-Napoca | 400015 | Romania | Details | |
| Local Institution - 0124 | NOT_YET_RECRUITING | Iași | 700106 | Romania | Details | |
| Local Institution - 0119 | NOT_YET_RECRUITING | Iași | 700483 | Romania | Details | |
| Local Institution - 0263 | NOT_YET_RECRUITING | Singapore | 169610 | Singapore | Details | |
| Local Institution - 0262 | NOT_YET_RECRUITING | Singapore | 308442 | Singapore | Details | |
| Local Institution - 0089 | NOT_YET_RECRUITING | Cheongju-si | Chungcheongbuk-do [Chungbuk] | 28644 | South Korea | Details |
| Local Institution - 0043 | NOT_YET_RECRUITING | Goyang-si | Kyǒnggi-do | 10408 | South Korea | Details |
| Local Institution - 0044 | NOT_YET_RECRUITING | Seongnam | Kyǒnggi-do | 13620 | South Korea | Details |
| Local Institution - 0046 | NOT_YET_RECRUITING | Suwon | Kyǒnggi-do | 16247 | South Korea | Details |
| Local Institution - 0095 | NOT_YET_RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 03080 | South Korea | Details |
| Local Institution - 0045 | NOT_YET_RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 03722 | South Korea | Details |
| Local Institution - 0092 | NOT_YET_RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 05505 | South Korea | Details |
| Local Institution - 0042 | NOT_YET_RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 06351 | South Korea | Details |
| Local Institution - 0218 | NOT_YET_RECRUITING | Barcelona | Barcelona [Barcelona] | 08035 | Spain | Details |
| Local Institution - 0177 | NOT_YET_RECRUITING | Barcelona | Catalunya [Cataluña] | 08041 | Spain | Details |
| Local Institution - 0175 | NOT_YET_RECRUITING | Madrid | Madrid, Comunidad de | 28009 | Spain | Details |
| Local Institution - 0206 | NOT_YET_RECRUITING | Madrid | Madrid, Comunidad de | 28041 | Spain | Details |
| Local Institution - 0176 | NOT_YET_RECRUITING | Madrid | Madrid, Comunidad de | 28046 | Spain | Details |
| Local Institution - 0181 | NOT_YET_RECRUITING | Majadahonda | Madrid, Comunidad de | 28222 | Spain | Details |
| Local Institution - 0178 | NOT_YET_RECRUITING | Málaga | 29011 | Spain | Details | |
| Local Institution - 0182 | NOT_YET_RECRUITING | Seville | 41013 | Spain | Details | |
| Local Institution - 0180 | NOT_YET_RECRUITING | Valencia | 46026 | Spain | Details | |
| Local Institution - 0179 | NOT_YET_RECRUITING | Zaragoza | 50009 | Spain | Details | |
| Kantonsspital Baden | RECRUITING | Baden | Canton of Aargau | 5404 | Switzerland | Details |
| Cantonal Hospital St.Gallen | RECRUITING | Sankt Gallen | Canton of St. Gallen | 9007 | Switzerland | Details |
| Local Institution - 0189 | NOT_YET_RECRUITING | Bellinzona | 6500 | Switzerland | Details | |
| Local Institution - 0053 | NOT_YET_RECRUITING | Kaohsiung City | 82445 | Taiwan | Details | |
| Taichung Veterans General Hospital | RECRUITING | Taichung | 407 | Taiwan | Details | |
| National Cheng Kung University Hospital | RECRUITING | Tainan | 704 | Taiwan | Details | |
| National Taiwan University Hospital | RECRUITING | Taipei | 10002 | Taiwan | Details | |
| Taipei Medical University Hospital | RECRUITING | Taipei | 110 | Taiwan | Details | |
| Taipei Veterans General Hospital | RECRUITING | Taipei | 11217 | Taiwan | Details | |
| Local Institution - 0265 | NOT_YET_RECRUITING | Bangkok | Bangkok | 10700 | Thailand | Details |
| Local Institution - 0272 | NOT_YET_RECRUITING | Mueng | Changwat Khon Kaen | 40002 | Thailand | Details |
| Local Institution - 0264 | NOT_YET_RECRUITING | Bangkok | 10330 | Thailand | Details | |
| Local Institution - 0266 | NOT_YET_RECRUITING | Songkhla | 90110 | Thailand | Details | |
| Local Institution - 0110 | NOT_YET_RECRUITING | Glasgow | Glasgow City | G12 0YN | United Kingdom | Details |
| Local Institution - 0061 | NOT_YET_RECRUITING | London | Kensington and Chelsea | SW3 6JJ | United Kingdom | Details |
| Local Institution - 0140 | NOT_YET_RECRUITING | London | London, City of | E1 1RD | United Kingdom | Details |
| Local Institution - 0281 | NOT_YET_RECRUITING | Sulton, Surrey | SM25PT | United Kingdom | Details |