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| NCT ID | NCT07106762 |
| Title | Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Bristol-Myers Squibb |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | SWE | ROU | NOR | NLD | ITA | ISR | IRL | GBR | FRA | ESP | DEU | CZE | CHE | CAN | BRA | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Local Institution - 0167 | NOT_YET_RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| Local Institution - 0162 | NOT_YET_RECRUITING | Fullerton | California | 92835 | United States | Details |
| Local Institution - 0252 | NOT_YET_RECRUITING | Palo Alto | California | 94304 | United States | Details |
| Local Institution - 0163 | NOT_YET_RECRUITING | Sacramento | California | 95816 | United States | Details |
| Local Institution - 0139 | NOT_YET_RECRUITING | Sacramento | California | 95817 | United States | Details |
| Local Institution - 0251 | NOT_YET_RECRUITING | San Francisco | California | 94115 | United States | Details |
| Local Institution - 0254 | NOT_YET_RECRUITING | Santa Rosa | California | 95403 | United States | Details |
| Local Institution - 0245 | WITHDRAWN | Dillon | Colorado | 80435 | United States | Details |
| Shaw Cancer Center | RECRUITING | Edwards | Colorado | 81632 | United States | Details |
| Local Institution - 0250 | NOT_YET_RECRUITING | Washington D.C. | District of Columbia | 20016 | United States | Details |
| Local Institution - 0247 | NOT_YET_RECRUITING | Miami | Florida | 33176 | United States | Details |
| Local Institution - 0193 | NOT_YET_RECRUITING | Lexington | Kentucky | 40536 | United States | Details |
| Local Institution - 0232 | NOT_YET_RECRUITING | Baltimore | Maryland | 21287 | United States | Details |
| Local Institution - 0195 | NOT_YET_RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Karmanos Cancer Institute | RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Local Institution - 0248 | NOT_YET_RECRUITING | Buffalo | New York | 14203 | United States | Details |
| Icahn School of Medicine at Mount Sinai | RECRUITING | New York | New York | 10029 | United States | Details |
| Memorial Sloan Kettering Cancer Center | RECRUITING | New York | New York | 10065 | United States | Details |
| Fairview Hospital | RECRUITING | Cleveland | Ohio | 44111 | United States | Details |
| Cleveland Clinic | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| Local Institution - 0161 | NOT_YET_RECRUITING | Columbus | Ohio | 43210 | United States | Details |
| Cleveland Clinic - Hillcrest Hospital | RECRUITING | Mayfield Heights | Ohio | 44124 | United States | Details |
| Local Institution - 0141 | NOT_YET_RECRUITING | Portland | Oregon | 97239 | United States | Details |
| Local Institution - 0186 | NOT_YET_RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Local Institution - 0084 | NOT_YET_RECRUITING | Nashville | Tennessee | 37232 | United States | Details |
| Local Institution - 0249 | NOT_YET_RECRUITING | Abilene | Texas | 79606 | United States | Details |
| Local Institution - 0187 | NOT_YET_RECRUITING | Austin | Texas | 78705 | United States | Details |
| Intermountain Medical Center | RECRUITING | Murray | Utah | 84107 | United States | Details |
| Local Institution - 0253 | NOT_YET_RECRUITING | St. George | Utah | 84790 | United States | Details |
| University of Virginia Health System | RECRUITING | Charlottesville | Virginia | 22903 | United States | Details |
| Local Institution - 0188 | NOT_YET_RECRUITING | Norfolk | Virginia | 23502 | United States | Details |
| Local Institution - 0200 | NOT_YET_RECRUITING | Seattle | Washington | 98101 | United States | Details |
| Local Institution - 0255 | NOT_YET_RECRUITING | Seattle | Washington | 98109 | United States | Details |
| Local Institution - 0028 | NOT_YET_RECRUITING | CABA | Buenos Aires | CP1280AEB | Argentina | Details |
| Local Institution - 0023 | NOT_YET_RECRUITING | Ciudad Autónoma de Buenos Aires | Buenos Aires | C1426ANZ | Argentina | Details |
| Local Institution - 0024 | NOT_YET_RECRUITING | ABB | Buenos Aires F.D. | C1199ABB | Argentina | Details |
| Local Institution - 0026 | NOT_YET_RECRUITING | Buenos Aires | Buenos Aires F.D. | C1419AHN | Argentina | Details |
| Local Institution - 0025 | NOT_YET_RECRUITING | Córdoba | 5000 | Argentina | Details | |
| Local Institution - 0027 | NOT_YET_RECRUITING | Mendoza | M5500AYB | Argentina | Details | |
| Macquarie University | RECRUITING | Macquarie University | New South Wales | 2109 | Australia | Details |
| GenesisCare North Shore | RECRUITING | St Leonards | New South Wales | 2065 | Australia | Details |
| Austin Health | RECRUITING | Heidelberg | Victoria | 3084 | Australia | Details |
| Local Institution - 0155 | NOT_YET_RECRUITING | Innsbruck | Tyrol | 6020 | Austria | Details |
| Medizinische Universität Wien | RECRUITING | Vienna | Vienna | 1090 | Austria | Details |
| Local Institution - 0131 | NOT_YET_RECRUITING | Vienna | Vienna | 1160 | Austria | Details |
| ZAS Augustinus | RECRUITING | Wilrijk | Antwerpen | 2610 | Belgium | Details |
| AZ Maria Middelares | RECRUITING | Ghent | Oost-Vlaanderen | 9000 | Belgium | Details |
| UZ Gent | RECRUITING | Ghent | Oost-Vlaanderen | 9000 | Belgium | Details |
| Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman | RECRUITING | Liège | 4000 | Belgium | Details | |
| Local Institution - 0129 | NOT_YET_RECRUITING | Salvador | Estado de Bahia | 41253-190 | Brazil | Details |
| Local Institution - 0121 | NOT_YET_RECRUITING | Porto Alegre | Rio Grande do Sul | 90610-000 | Brazil | Details |
| Local Institution - 0130 | NOT_YET_RECRUITING | Rio de Janeiro | 22451-100 | Brazil | Details | |
| Local Institution - 0124 | NOT_YET_RECRUITING | São Paulo | 01452-000 | Brazil | Details | |
| Local Institution - 0020 | NOT_YET_RECRUITING | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| The Ottawa Hospital Cancer Centre | RECRUITING | Ottawa | Ontario | K1H 8L6 | Canada | Details |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Local Institution - 0017 | NOT_YET_RECRUITING | Montreal | Quebec | H4A 3J1 | Canada | Details |
| Local Institution - 0050 | NOT_YET_RECRUITING | Beijing | Beijing Municipality | 100034 | China | Details |
| Local Institution - 0224 | NOT_YET_RECRUITING | Beijing | Beijing Municipality | 100091 | China | Details |
| Local Institution - 0048 | NOT_YET_RECRUITING | Fuzhou | Fujian | 350001 | China | Details |
| Local Institution - 0060 | NOT_YET_RECRUITING | Fuzhou | Fujian | 350005 | China | Details |
| Local Institution - 0056 | NOT_YET_RECRUITING | Xiamen | Fujian | 361003 | China | Details |
| Local Institution - 0051 | NOT_YET_RECRUITING | Guangzhou | Guangdong | 510060 | China | Details |
| The First Affiliated Hospital of Guangzhou Medical University | RECRUITING | Guangzhou | Guangdong | 510120 | China | Details |
| Local Institution - 0226 | NOT_YET_RECRUITING | Guangzhou | Guangdong | 510280 | China | Details |
| Local Institution - 0201 | NOT_YET_RECRUITING | Wuhan | Hubei | 430030 | China | Details |
| Local Institution - 0059 | NOT_YET_RECRUITING | Changsha | Hunan | 410013 | China | Details |
| Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School | RECRUITING | Nanjing | Jiangsu | 210000 | China | Details |
| Local Institution - 0046 | NOT_YET_RECRUITING | Nanjing | Jiangsu | 210009 | China | Details |
| Local Institution - 0114 | NOT_YET_RECRUITING | Nantong | Jiangsu | 226361 | China | Details |
| Local Institution - 0206 | NOT_YET_RECRUITING | Nanchang | Jiangxi | 330006 | China | Details |
| Shandong Cancer Hospital | RECRUITING | Jinan | Shandong | 250117 | China | Details |
| Local Institution - 0156 | NOT_YET_RECRUITING | Qingdao | Shandong | 266003 | China | Details |
| Local Institution - 0205 | NOT_YET_RECRUITING | Yantai | Shandong | 264000 | China | Details |
| Local Institution - 0042 | NOT_YET_RECRUITING | Shanghai | Shanghai Municipality | 200032 | China | Details |
| West China Hospital, Sichuan University | RECRUITING | Chengdu | Sichuan | 610066 | China | Details |
| Local Institution - 0052 | NOT_YET_RECRUITING | Tianjin | Tianjin Municipality | 300060 | China | Details |
| Local Institution - 0227 | NOT_YET_RECRUITING | Tianjin | Tianjin Municipality | 300070 | China | Details |
| Local Institution - 0157 | NOT_YET_RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Local Institution - 0053 | NOT_YET_RECRUITING | Wenzhou | Zhejiang | 325000 | China | Details |
| Local Institution - 0064 | NOT_YET_RECRUITING | Zhengzhou | 450008 | China | Details | |
| Local Institution - 0115 | NOT_YET_RECRUITING | Brno | Brno-město | 656 53 | Czechia | Details |
| Local Institution - 0146 | NOT_YET_RECRUITING | Hradec Králové | Hradec Králové | 500 05 | Czechia | Details |
| Local Institution - 0041 | NOT_YET_RECRUITING | Prague | Praha 5 | 150 06 | Czechia | Details |
| Local Institution - 0009 | NOT_YET_RECRUITING | Nice | Alpes-Maritimes | 06189 | France | Details |
| Local Institution - 0040 | NOT_YET_RECRUITING | Strasbourg | Alsace | 67098 | France | Details |
| CHU de Bordeaux Hop St ANDRE | RECRUITING | Bordeaux | Aquitaine | 33075 | France | Details |
| Local Institution - 0006 | NOT_YET_RECRUITING | Lyon Cedex08 | Auvergne-Rhône-Alpes | 69373 | France | Details |
| Local Institution - 0258 | NOT_YET_RECRUITING | Brest | Finistère | 29200 | France | Details |
| Local Institution - 0223 | NOT_YET_RECRUITING | Suresnes | Hauts-de-Seine | 92151 | France | Details |
| Local Institution - 0002 | NOT_YET_RECRUITING | Saint-Herblain | Loire-Atlantique | 44805 | France | Details |
| Local Institution - 0005 | WITHDRAWN | Marseille | Provence-Alpes-Côte d'Azur Region | 13273 | France | Details |
| Local Institution - 0003 | NOT_YET_RECRUITING | Clermont-Ferrand | Puy-de-Dôme | 63011 | France | Details |
| Local Institution - 0001 | NOT_YET_RECRUITING | Villejuif | Val-de-Marne | 94800 | France | Details |
| Local Institution - 0008 | NOT_YET_RECRUITING | Paris | 75015 | France | Details | |
| Groupe hospitalier Paris saint Joseph | RECRUITING | Paris | Île-de-France Region | 75014 | France | Details |
| NCT | RECRUITING | Heidelberg | Baden-Wurttemberg | 69120 | Germany | Details |
| Studienpraxis Urologie | RECRUITING | Nürtingen | Baden-Wurttemberg | 72622 | Germany | Details |
| TUM Klinikum | RECRUITING | Munich | Bavaria | 81675 | Germany | Details |
| Klinikum Nürnberg Nord | RECRUITING | Nuremberg | Bavaria | 90419 | Germany | Details |
| Caritas-Krankenhaus St. Josef | RECRUITING | Regensburg | Bavaria | 93053 | Germany | Details |
| Medizinische Hochschule Hannover | RECRUITING | Hanover | Lower Saxony | 30625 | Germany | Details |
| Universitaetsklinikum Schleswig-Holstein Campus Kiel | RECRUITING | Kiel | Schleswig-Holstein | 24105 | Germany | Details |
| Universitätsklinikum Jena | RECRUITING | Jena | Thuringia | 07747 | Germany | Details |
| Local Institution - 0154 | NOT_YET_RECRUITING | Berlin | 10117 | Germany | Details | |
| Universitaetsklinikum Duesseldorf | RECRUITING | Düsseldorf | 40225 | Germany | Details | |
| Krankenhaus Nordwest GmbH | RECRUITING | Frankfurt | 60488 | Germany | Details | |
| Universitaetsklinikum Hamburg-Eppendorf | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Marienhospital Herne | RECRUITING | Herne | 44625 | Germany | Details | |
| Universitaetsklinikum Ulm | RECRUITING | Ulm | 89081 | Germany | Details | |
| Local Institution - 0238 | NOT_YET_RECRUITING | Cork | T12 DC4A | Ireland | Details | |
| Local Institution - 0236 | NOT_YET_RECRUITING | Dublin | D24 NR0A | Ireland | Details | |
| Local Institution - 0096 | NOT_YET_RECRUITING | Petah Tikva | Central District | 4941492 | Israel | Details |
| Local Institution - 0106 | NOT_YET_RECRUITING | Ẕerifin | Central District | 70300 | Israel | Details |
| Local Institution - 0095 | NOT_YET_RECRUITING | Jerusalem | Jerusalem | 9112001 | Israel | Details |
| Local Institution - 0094 | NOT_YET_RECRUITING | Haifa | Northern District | 3109601 | Israel | Details |
| A.O.U.C. Policlinico di Bari | RECRUITING | Bari | Apulia | 70124 | Italy | Details |
| Local Institution - 0099 | NOT_YET_RECRUITING | Genoa | Liguria | 16132 | Italy | Details |
| Istituto Nazionale Tumori Regina Elena | RECRUITING | Rome | Roma | 00144 | Italy | Details |
| Local Institution - 0100 | NOT_YET_RECRUITING | Pisa | Tuscany | 56126 | Italy | Details |
| Istituto Oncologico Veneto IRCCS | RECRUITING | Castelfranco Veneto | Veneto | 31033 | Italy | Details |
| Fondazione IRCCS Istituto Nazionale dei Tumori | RECRUITING | Milan | 20133 | Italy | Details | |
| Ospedale San Raffaele | RECRUITING | Milan | 20132 | Italy | Details | |
| Azienda Ospedaliera Universitaria Federico II | RECRUITING | Naples | 80131 | Italy | Details | |
| Local Institution - 0098 | NOT_YET_RECRUITING | Parma | 43126 | Italy | Details | |
| Local Institution - 0183 | NOT_YET_RECRUITING | Kawasaki | Kanagawa | 216-8511 | Japan | Details |
| Local Institution - 0171 | NOT_YET_RECRUITING | Bunkyo-ku | Tokyo | 1138603 | Japan | Details |
| Local Institution - 0169 | NOT_YET_RECRUITING | Koto-ku | Tokyo | 135-8550 | Japan | Details |
| Local Institution - 0179 | NOT_YET_RECRUITING | Toyoma | Toyama | 930-0194 | Japan | Details |
| Local Institution - 0036 | NOT_YET_RECRUITING | Breda | North Brabant | 4818 CK | Netherlands | Details |
| Local Institution - 0033 | NOT_YET_RECRUITING | Amsterdam | North Holland | 1066 CX | Netherlands | Details |
| Local Institution - 0031 | NOT_YET_RECRUITING | Leeuwarden | Provincie Friesland | 8934 AD | Netherlands | Details |
| Akershus Universitetssykehus | RECRUITING | Lørenskog | Akershus | 1478 | Norway | Details |
| Sykehuset i Vestfold | RECRUITING | Tønsberg | Vestfold | 3103 | Norway | Details |
| Sykehuset Østfold Kalnes | RECRUITING | Sarpsborg | Østfold fylke | 1714 | Norway | Details |
| Centrul de Oncologie "Sfântul Nectarie" | RECRUITING | Craiova | Dolj | 200542 | Romania | Details |
| Local Institution - 0066 | NOT_YET_RECRUITING | Cluj-Napoca | 400015 | Romania | Details | |
| Institutul Regional de Oncologie | RECRUITING | Iași | 700483 | Romania | Details | |
| Hospital Universitario Marqués de Valdecilla | RECRUITING | Santander | Cantabria | 39008 | Spain | Details |
| Hospital de la Santa Creu i Sant Pau | RECRUITING | Barcelona | Catalunya [Cataluña] | 08041 | Spain | Details |
| Hospital Universitario Ramón y Cajal | RECRUITING | Madrid | Madrid, Comunidad de | 28034 | Spain | Details |
| Local Institution - 0199 | NOT_YET_RECRUITING | Valencia | Valenciana, Comunitat | 46009 | Spain | Details |
| Hospital Infanta Cristina | RECRUITING | Badajoz | 06006 | Spain | Details | |
| Hospital Universitario Reina Sofia | RECRUITING | Córdoba | 14004 | Spain | Details | |
| Hospital Clinico San Carlos | RECRUITING | Madrid | 28040 | Spain | Details | |
| Hospital Universitario Virgen Del Rocio | RECRUITING | Seville | 41013 | Spain | Details | |
| Local Institution - 0235 | NOT_YET_RECRUITING | Solna | Stockholms Län [se-01] | 171 64 | Sweden | Details |
| Local Institution - 0234 | NOT_YET_RECRUITING | Gothenburg | Västra Götalands Län [se-14] | 413 45 | Sweden | Details |
| Local Institution - 0241 | NOT_YET_RECRUITING | Malmo | 205 02 | Sweden | Details | |
| Cantonal Hospital St.Gallen | RECRUITING | Sankt Gallen | Canton of St. Gallen | 9007 | Switzerland | Details |
| Ospedale Regionale Bellinzona e Valli | RECRUITING | Bellinzona | Canton Ticino | 6500 | Switzerland | Details |
| Kantonsspital Graubünden | RECRUITING | Chur | 7000 | Switzerland | Details | |
| UniversitätsSpital Zürich | RECRUITING | Zurich | 8091 | Switzerland | Details | |
| Local Institution - 0243 | NOT_YET_RECRUITING | Glasgow | Glasgow City | G12 0YN | United Kingdom | Details |
| St Bartholomew's Hospital | RECRUITING | London | London, City of | EC1A 7BE | United Kingdom | Details |
| Royal Marsden Hospital (Sutton) | RECRUITING | London | Sutton | SM2 5PT | United Kingdom | Details |
| Local Institution - 0230 | NOT_YET_RECRUITING | Sheffield | S10 2SJ | United Kingdom | Details |