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| NCT ID | NCT07680790 |
| Title | Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02) |
| Recruitment | Not yet recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Bristol-Myers Squibb |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | ITA | FRA | ESP | DEU | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Local Institution - 0212 | Beverly Hills | California | 90211 | United States | Details | |
| Local Institution - 0504 | Fullerton | California | 92835 | United States | Details | |
| Local Institution - 0357 | La Jolla | California | 92093 | United States | Details | |
| Local Institution - 0520 | Pueblo | Colorado | 81003 | United States | Details | |
| Local Institution - 0366 | Orlando | Florida | 32806 | United States | Details | |
| Local Institution - 0519 | Palm Bay | Florida | 32901 | United States | Details | |
| Local Institution - 0210 | Honolulu | Hawaii | 96813 | United States | Details | |
| Local Institution - 0207 | Ottawa | Illinois | 61350 | United States | Details | |
| Local Institution - 0503 | Baltimore | Maryland | 21202 | United States | Details | |
| Local Institution - 0523 | Silver Spring | Maryland | 20904 | United States | Details | |
| Local Institution - 0521 | Edina | Minnesota | 55435 | United States | Details | |
| Local Institution - 0364 | Saint Paul | Minnesota | 55102 | United States | Details | |
| Local Institution - 0403 | St Louis | Missouri | 63110 | United States | Details | |
| Local Institution - 0402 | Omaha | Nebraska | 68198 | United States | Details | |
| Local Institution - 0290 | Lebanon | New Hampshire | 03756 | United States | Details | |
| Local Institution - 0183 | New Brunswick | New Jersey | 08901 | United States | Details | |
| Local Institution - 0153 | New York | New York | 10021 | United States | Details | |
| Local Institution - 0157 | The Bronx | New York | 10461 | United States | Details | |
| Local Institution - 0385 | Charlotte | North Carolina | 28204 | United States | Details | |
| Local Institution - 0438 | Sandusky | Ohio | 44870 | United States | Details | |
| Local Institution - 0404 | Portland | Oregon | 97213 | United States | Details | |
| Local Institution - 0487 | Easton | Pennsylvania | 18045 | United States | Details | |
| Local Institution - 0200 | Sioux Falls | South Dakota | 57105 | United States | Details | |
| Local Institution - 0199 | Memphis | Tennessee | 38120 | United States | Details | |
| Local Institution - 0522 | Beaumont | Texas | 77702 | United States | Details | |
| Local Institution - 0525 | Dallas | Texas | 75246 | United States | Details | |
| Local Institution - 0529 | San Antonio | Texas | 78217 | United States | Details | |
| Local Institution - 0411 | Salt Lake City | Utah | 84112 | United States | Details | |
| Local Institution - 0165 | Fairfax | Virginia | 22031 | United States | Details | |
| Local Institution - 0530 | Fairfax | Virginia | 22031 | United States | Details | |
| Local Institution - 0528 | Winchester | Virginia | 22601 | United States | Details | |
| Local Institution - 0283 | Seattle | Washington | 98104 | United States | Details | |
| Local Institution - 0502 | Morgantown | West Virginia | 26505 | United States | Details | |
| Local Institution - 0424 | Camperdown | New South Wales | 2050 | Australia | Details | |
| Local Institution - 0439 | Westmead | New South Wales | 2145 | Australia | Details | |
| Local Institution - 0511 | Greenslopes | Queensland | 4120 | Australia | Details | |
| Local Institution - 0492 | Adelaide | South Australia | 5000 | Australia | Details | |
| Local Institution - 0447 | Clayton | Victoria | 3168 | Australia | Details | |
| Local Institution - 0437 | Murdoch | Western Australia | 6150 | Australia | Details | |
| Local Institution - 0059 | Edmonton | Alberta | T6G1Z2 | Canada | Details | |
| Local Institution - 0494 | Abbotsford British Columbia | British Columbia | V2S0C2 | Canada | Details | |
| Local Institution - 0056 | Vancouver | British Columbia | V5Z4E6 | Canada | Details | |
| Local Institution - 0533 | Oakville | Ontario | L6M 0L8 | Canada | Details | |
| Local Institution - 0043 | Oshawa | Ontario | L1G2B9 | Canada | Details | |
| Local Institution - 0012 | Toronto | Ontario | M4N3M5 | Canada | Details | |
| Local Institution - 0045 | Toronto | Ontario | M5G2M9 | Canada | Details | |
| Local Institution - 0407 | Laval | Quebec | H7M3L9 | Canada | Details | |
| Local Institution - 0058 | Montreal | Quebec | H3T1E2 | Canada | Details | |
| Local Institution - 0057 | Montreal | Quebec | H4A3J1 | Canada | Details | |
| Local Institution - 0040 | Regina | Saskatchewan | S4T1A5 | Canada | Details | |
| Local Institution - 0517 | Beijing | Beijing Municipality | 100142 | China | Details | |
| Local Institution - 0458 | Beijing | Beijing Municipality | 101149 | China | Details | |
| Local Institution - 0470 | Chongqing | Chongqing Municipality | 400030 | China | Details | |
| Local Institution - 0493 | Fuzhou | Fujian | 350001 | China | Details | |
| Local Institution - 0457 | Fuzhou | Fujian | 350014 | China | Details | |
| Local Institution - 0326 | Dongguan Shi | Guangdong | 523059 | China | Details | |
| Local Institution - 0331 | Guangzhou | Guangdong | 510080 | China | Details | |
| Local Institution - 0478 | Zhongshan | Guangdong | 528403 | China | Details | |
| Local Institution - 0321 | Guilin | Guangxi | 541199 | China | Details | |
| Local Institution - 0328 | Nanning | Guangxi | 530021 | China | Details | |
| Local Institution - 0330 | Haikou | Hainan | 570000 | China | Details | |
| Local Institution - 0343 | Harbin | Heilongjiang | 150081 | China | Details | |
| Local Institution - 0341 | Weihui Shi | Henan | 453100 | China | Details | |
| Local Institution - 0480 | Zhengzhou | Henan | 450000 | China | Details | |
| Local Institution - 0423 | Zhengzhou | Henan | 450008 | China | Details | |
| Local Institution - 0483 | Jingzhou | Hubei | 0 | China | Details | |
| Local Institution - 0450 | Wuhan | Hubei | 430022 | China | Details | |
| Local Institution - 0482 | Changsha | Hunan | 410007 | China | Details | |
| Local Institution - 0467 | Changsha Shi | Hunan | 410008 | China | Details | |
| Local Institution - 0306 | Changsha Shi | Hunan | 410013 | China | Details | |
| Local Institution - 0347 | Nanjing | Jiangsu | 210029 | China | Details | |
| Local Institution - 0332 | Shenyang | Liaoning | 110042 | China | Details | |
| Local Institution - 0464 | Xi'an | Shaanxi | 710038 | China | Details | |
| Local Institution - 0479 | Binzhou | Shandong | 256603 | China | Details | |
| Local Institution - 0469 | Weifang Shi | Shandong | 261000 | China | Details | |
| Local Institution - 0319 | Shanghai Shi | Shanghai Municipality | 200120 | China | Details | |
| Local Institution - 0316 | Taiyuan | Shanxi | 30001 | China | Details | |
| Local Institution - 0463 | Taiyuan | Shanxi | 30013 | China | Details | |
| Local Institution - 0456 | Chengdu | Sichuan | 610041 | China | Details | |
| Local Institution - 0471 | Chengdu | Sichuan | 610041 | China | Details | |
| Local Institution - 0320 | Dazhou Shi | Sichuan | 635000 | China | Details | |
| Local Institution - 0472 | Yibin | Sichuan | 644000 | China | Details | |
| Local Institution - 0452 | Tianjin | Tianjin Municipality | 300060 | China | Details | |
| Local Institution - 0312 | Hangzhou | Zhejiang | 310022 | China | Details | |
| Local Institution - 0074 | Marseille | Bouches-Du-Rhône | 13915 | France | Details | |
| Local Institution - 0063 | Dijon | Côte-D'Or | 21079 | France | Details | |
| Local Institution - 0075 | Nantes | Loire Atlantique | 44093 | France | Details | |
| Local Institution - 0064 | La Tronche | Nan | 38700 | France | Details | |
| Local Institution - 0116 | Lyon | Nan | 69373 | France | Details | |
| Local Institution - 0109 | Paris | Nan | 75014 | France | Details | |
| Local Institution - 0062 | Bron | Rhône | 69677 | France | Details | |
| Local Institution - 0069 | Villejuif | Val-De-Marne | 94805 | France | Details | |
| Local Institution - 0073 | Brest | 29200 | France | Details | ||
| Local Institution - 0066 | Caen | 14076 | France | Details | ||
| Local Institution - 0070 | Toulouse | 31059 | France | Details | ||
| Local Institution - 0071 | Paris | Île-de-France Region | 75248 | France | Details | |
| Local Institution - 0112 | Gerlingen | Baden-Wurttemberg | 70839 | Germany | Details | |
| Local Institution - 0111 | Ulm | Baden-Wurttemberg | 89081 | Germany | Details | |
| Local Institution - 0110 | Wangen | Baden-Wurttemberg | 88239 | Germany | Details | |
| Local Institution - 0001 | Munich | Bavaria | 81377 | Germany | Details | |
| Local Institution - 0105 | Regensburg | Bavaria | 93053 | Germany | Details | |
| Local Institution - 0446 | Frankfurt am Main | Hesse | 60389 | Germany | Details | |
| Local Institution - 0106 | Oldenburg | Lower Saxony | 26121 | Germany | Details | |
| Local Institution - 0100 | Cologne | North Rhine-Westphalia | 50937 | Germany | Details | |
| Local Institution - 0243 | Dortmund | North Rhine-Westphalia | 44263 | Germany | Details | |
| Local Institution - 0104 | Essen | North Rhine-Westphalia | 45147 | Germany | Details | |
| Local Institution - 0117 | Hemer | North Rhine-Westphalia | 58675 | Germany | Details | |
| Local Institution - 0101 | Münster | North Rhine-Westphalia | 48149 | Germany | Details | |
| Local Institution - 0103 | Dresden | Saxony | 1307 | Germany | Details | |
| Local Institution - 0412 | Leipzig | Saxony | 4103 | Germany | Details | |
| Local Institution - 0108 | Großhansdorf | Schleswig-Holstein | 22927 | Germany | Details | |
| Local Institution - 0239 | Lübeck | Schleswig-Holstein | 23538 | Germany | Details | |
| Local Institution - 0445 | Giessen | 35392 | Germany | Details | ||
| Local Institution - 0225 | Vadodara | Gujarat | 361790 | India | Details | |
| Local Institution - 0444 | Badsa | Haryana | 124105 | India | Details | |
| Local Institution - 0337 | Gurgaon | Haryana | 122001 | India | Details | |
| Local Institution - 0436 | Belagavi | Karnataka | 590010 | India | Details | |
| Local Institution - 0215 | Pune | Maharashtra | 411013 | India | Details | |
| Local Institution - 0233 | Mohali | Punjab | 140901 | India | Details | |
| Local Institution - 0222 | Chennai | Tamil Nadu | 600035 | India | Details | |
| Local Institution - 0236 | Meldola | Forli-Cesena | 47014 | Italy | Details | |
| Local Institution - 0094 | Candiolo | Turin | 10060 | Italy | Details | |
| Local Institution - 0093 | Bergamo | 24128 | Italy | Details | ||
| Local Institution - 0289 | Brescia | 25123 | Italy | Details | ||
| Local Institution - 0089 | Milan | 20133 | Italy | Details | ||
| Local Institution - 0087 | Milan | 20141 | Italy | Details | ||
| Local Institution - 0238 | Milan | 20142 | Italy | Details | ||
| Local Institution - 0091 | Pavia | 27100 | Italy | Details | ||
| Local Institution - 0088 | Verona | 37126 | Italy | Details | ||
| Local Institution - 0262 | Nagoya | Aichi-ken | 464-8681 | Japan | Details | |
| Local Institution - 0128 | Toon-Shi | Ehime | 791-0295 | Japan | Details | |
| Local Institution - 0136 | Kurume-Shi | Fukuoka | 830-0011 | Japan | Details | |
| Local Institution - 0121 | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Local Institution - 0122 | Sendai | Miyagi | 980-0873 | Japan | Details | |
| Local Institution - 0433 | Okayama | Okayama-ken | 700-8558 | Japan | Details | |
| Local Institution - 0125 | Hirakata-Shi | Osaka | 573-1191 | Japan | Details | |
| Local Institution - 0129 | Osakasayama-Shi | Osaka | 589-8511 | Japan | Details | |
| Local Institution - 0141 | Hamamatsu | Shizuoka | 431-3192 | Japan | Details | |
| Local Institution - 0137 | Chūōku | Tokyo-To | 104-0045 | Japan | Details | |
| Local Institution - 0414 | Kōtoku | Tokyo-To | 135-8550 | Japan | Details | |
| Local Institution - 0138 | Buk-Gu | Daegu | 41404 | South Korea | Details | |
| Local Institution - 0506 | Dalseo | Daegu | 42601 | South Korea | Details | |
| Local Institution - 0127 | Goyang-si | Gyeonggi-do | 410-769 | South Korea | Details | |
| Local Institution - 0133 | Seongnam-si | Gyeonggi-do | 13620 | South Korea | Details | |
| Local Institution - 0134 | Hwasun-Gun | Jeollanam-do | 58128 | South Korea | Details | |
| Local Institution - 0140 | Cheongju-si | North Chungcheong | 361-711 | South Korea | Details | |
| Local Institution - 0124 | Seocho -Gu | Seoul | 6591 | South Korea | Details | |
| Local Institution - 0123 | Songpa-Gu | Seoul | 138-736 | South Korea | Details | |
| Local Institution - 0139 | Gyeongsangnam-do | 050612 | South Korea | Details | ||
| Local Institution - 0135 | Seoul | 120-752 | South Korea | Details | ||
| Local Institution - 0131 | Seoul | 3080 | South Korea | Details | ||
| Local Institution - 0126 | Seoul | 8308 | South Korea | Details | ||
| Local Institution - 0143 | Majadahonda | Madrid | 28222 | Spain | Details | |
| Local Institution - 0147 | Seville | Seville | 41013 | Spain | Details | |
| Local Institution - 0242 | A Coruña | 15006 | Spain | Details | ||
| Local Institution - 0144 | Jaén | 23007 | Spain | Details | ||
| Local Institution - 0226 | Jaén | 23007 | Spain | Details | ||
| Local Institution - 0149 | Jerez de la Frontera | 11407 | Spain | Details | ||
| Local Institution - 0148 | Madrid | 28041 | Spain | Details | ||
| Local Institution - 0150 | Málaga | 29010 | Spain | Details | ||
| Local Institution - 0241 | Valencia | 46009 | Spain | Details | ||
| Local Institution - 0229 | Kaohsiung City | Kaohsiung | 82445 | Taiwan | Details | |
| Local Institution - 0230 | New Taipei City | New Taipei | 23561 | Taiwan | Details | |
| Local Institution - 0216 | Taipei | Taichung | 112 | Taiwan | Details | |
| Local Institution - 0227 | Gaoxiongka | Taiwan | 807 | Taiwan | Details | |
| Local Institution - 0221 | Taoyuan City | Taoyuan | 33378 | Taiwan | Details | |
| Local Institution - 0418 | Taichung | 40201 | Taiwan | Details | ||
| Local Institution - 0420 | Tainan | 70428 | Taiwan | Details | ||
| Local Institution - 0419 | Taipei | 100225 | Taiwan | Details | ||
| Local Institution - 0021 | Sur | Diyarbakır | 21200 | Turkey (Türkiye) | Details | |
| Local Institution - 0265 | Pendik | Istanbul | 34340 | Turkey (Türkiye) | Details | |
| Local Institution - 0014 | Adana | 1060 | Turkey (Türkiye) | Details | ||
| Local Institution - 0019 | Adana | 1370 | Turkey (Türkiye) | Details | ||
| Local Institution - 0008 | Ankara | 6680 | Turkey (Türkiye) | Details | ||
| Local Institution - 0003 | Ankara | 6800 | Turkey (Türkiye) | Details | ||
| Local Institution - 0015 | Antalya | 07100 | Turkey (Türkiye) | Details | ||
| Local Institution - 0041 | Istanbul | 34214 | Turkey (Türkiye) | Details | ||
| Local Institution - 0039 | Istanbul | 34295 | Turkey (Türkiye) | Details | ||
| Local Institution - 0050 | Izmir | 35110 | Turkey (Türkiye) | Details | ||
| Local Institution - 0037 | Izmir | 35530 | Turkey (Türkiye) | Details |