Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | BPX-603 |
| Trade Name | |
| Synonyms | HER-2 Autologous GoCAR-T|BPX603|BPX 603 |
| Drug Descriptions |
BPX-603 are autologous T lymphocytes engineered to express a chimeric antigen receptor (CAR) for ERBB2 (HER2) and a dual-switch consisting of chemical inducer of dimerization (CID)-inducible co-activation domain (MyD88/CD40) and an inducible caspase 9 safety switch (CaspaCIDe), which may lead to activation of anti-tumor immune responses in the tumor microenvironment (NCI Drug Dictionary). |
| DrugClasses | HER2 (ERBB2) Immune Cell Therapy 9 |
| CAS Registry Number | NA |
| NCIT ID | C176990 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BPX-603 | BPX-603 | 0 | 0 |