AC480
Drug Detail
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| Drug Name | AC480 |
| Trade Name | |
| Synonyms | BMS-599626|AC-480 |
| Drug Descriptions |
AC480 (BMS-599626) is an inhibitor of EGFR and ERBB2 (HER2), which may prevent downstream signaling and inhibit the proliferation of tumor cells that overexpress these receptors (PMID: 17062696, PMID: 21576284). |
| DrugClasses | EGFR Inhibitor (Pan) 63 HER2 Inhibitor 44 |
| CAS Registry Number | 714971-09-2 |
| NCIT ID | C48380 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AC480 | AC480 | 0 | 0 |
| AC480 + Doxorubicin | AC480 Doxorubicin | 0 | 0 |
| AC480 + Mitoxantrone | AC480 Mitoxantrone | 0 | 0 |
| AC480 + Topotecan | AC480 Topotecan | 0 | 0 |
| AC480 + Vincristine Sulfate | AC480 Vincristine Sulfate | 0 | 0 |
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