MGD013
Drug Detail
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| Drug Name | MGD013 |
| Trade Name | |
| Synonyms | MGD-013|Tebotelimab |
| Drug Descriptions |
MGD013 is an engineered antibody protein that targets both PDCD1 (PD-1) and LAG3 resulting in enhanced T-cell mediated anti-tumor immune response (Cancer Res July 15 2016 (76) (14 Supplement) 3217). |
| DrugClasses | Immune Checkpoint Inhibitor 150 LAG3 Antibody 19 PD-L1/PD-1 antibody 132 |
| CAS Registry Number | NA |
| NCIT ID | C143957 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Capecitabine + Margetuximab-cmkb + MGD013 + Oxaliplatin | Capecitabine MGD013 Margetuximab-cmkb Oxaliplatin | 0 | 1 |
| Enoblituzumab + MGD013 | Enoblituzumab MGD013 | 0 | 1 |
| Fluorouracil + Leucovorin + Margetuximab-cmkb + MGD013 + Oxaliplatin | Fluorouracil Leucovorin MGD013 Margetuximab-cmkb Oxaliplatin | 0 | 1 |
| Margetuximab-cmkb + MGD013 | MGD013 Margetuximab-cmkb | 0 | 0 |
| MGD013 | MGD013 | 0 | 1 |
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