Gene Detail
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| Gene Symbol | CDH2 | ||||||||||
| Synonyms | ACOGS | ADHD8 | ARVD14 | CD325 | CDHN | CDw325 | NCAD | ||||||||||
| Gene Description | CDH2, cadherin 2, encodes N-Cadherin, an extracellular matrix protein that plays a significant role in cell migration and invasion, especially during embryonic development (PMID: 15349821). CDH2 has been shown to be either upregulated or overexpressed in a variety of cancer types including, but not limited to melanoma, and, downregulation of CDH2 has been observed in neuroblastoma (PMID: 24442140). | ||||||||||
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