Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol CDH2
Synonyms ACOGS | ADHD8 | ARVD14 | CD325 | CDHN | CDw325 | NCAD
Gene Description CDH2, cadherin 2, encodes N-Cadherin, an extracellular matrix protein that plays a significant role in cell migration and invasion, especially during embryonic development (PMID: 15349821). CDH2 has been shown to be either upregulated or overexpressed in a variety of cancer types including, but not limited to melanoma, and, downregulation of CDH2 has been observed in neuroblastoma (PMID: 24442140).
Additional content available in CKB BOOST