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Gene Symbol TANK
Synonyms I-TRAF | ITRAF | TRAF2
Gene Description TANK, TRAF family member associated NFKB activator, interacts with TRAF proteins and other protein binding partners, and plays a role in regulation of NF-KappaB signaling (PMID: 25861989, PMID: 23139637, PMID: 20484576). A TANK-BRAF fusion has been identified in thyroid papillary carcinoma (PMID: 26314551) and a TANK-NTRK2 has been identified in melanoma (PMID: 28719467).
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