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Gene Symbol CDH11
Synonyms CAD11 | CDHOB | ESWS | OB | OSF-4 | TBHS2
Gene Description CDH11, cadherin 11, is a cell adhesion molecule and type II cadherin, which regulates mesenchymal stem cell differentiation and tissue morphogenesis, and plays a role in inflammatory response (PMID: 23657489, PMID: 25771201). Overexpression of Cdh11 is associated with poor recurrence-free survival in breast cancer patients (PMID: 24810778), and hypermethylation of the CDH11 promoter is commonly observed in many cancers, including breast, hepatocellular, and gastric carcinomas (PMID: 22139084).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
1009 16 16q21 NM_001797 Tumor suppressor (PMID: 30606230)
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