CDK8 - Gene Detail
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| Gene Symbol | CDK8 | ||||||||||||
| Synonyms | IDDHBA | K35 | ||||||||||||
| Gene Description | CDK8, cyclin dependent kinase 8, encodes for a member of the mediator complex that binds cyclin-C (CCNC) to regulate gene expression through transcription (PMID: 24043446, PMID: 32071145, PMID: 31248103). Overexpression and/or amplification of CDK8 has been associated with colorectal cancer (PMID: 18794900), gastric cancer, breast cancer, melanoma (PMID: 32206448), and prostate cancer (PMID: 31382571). | ||||||||||||
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