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Gene Symbol STAG1
Synonyms MRD47 | SA1 | SCC3A
Gene Description STAG1, stromal antigen 1, encodes a component of the cohesin complex, and plays a role in telomeric chromatin cohesion, apoptosis, DNA repair, and regulation of gene expression (PMID: 24856830, PMID: 27207471, PMID: 15361841). STAG1 mutations have been identified in several tumor types including acute myeloid leukemia (PMID: 24856830, PMID: 24335498), and bladder cancer (PMID: 27207471).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
10274 3 3q22.3 NM_005862 Tumor suppressor (PMID: 30606230)
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