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Gene Symbol | TRDN | ||||||||||
Synonyms | CARDAR | CPVT5 | TDN | TRISK | ||||||||||
Gene Description | TRDN, triadin, encodes a protein that plays a role in calcium release from ion channels in cardiac muscle, thereby contributing to muscle contraction and maintenance of a regular heart rhythm (PMID: 19383796, PMID: 17569730), and skeletal muscle function (PMID: 19843516). TRDN mutations have been associated with Burkitt's lymphoma (PMID: 30779244) and osteosarcoma (PMID: 26787232). | ||||||||||
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