ZMYND11 - Gene Detail
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| Gene Symbol | ZMYND11 | ||||||||||||
| Synonyms | BRAM1 | BS69 | MRD30 | ||||||||||||
| Gene Description | ZMYND11, zinc finger MYND-type containing 11, is an H3.3-specific histone reader and functions as a transcriptional co-repressor (PMID: 24590075, PMID: 11244510, PMID: 24795016). An FGFR2-ZMYND11 fusion has been identified in cholangiocarcinoma (PMID: 37541273), a ZYMND11-MBTD1 fusion has been observed in acute myeloid leukemia (PMID: 26608508), and down-regulation of Zmynd11 has been observed in multiple tumor types (PMID: 39341825), including breast cancer (PMID: 24590075) and glioblastoma (PMID: 29066350). | ||||||||||||
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