Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PNRC1
Synonyms B4-2 | PNAS-145 | PROL2 | PRR2
Gene Description PNRC1, proline rich nuclear receptor coactivator 1, acts as a co-activator for nuclear receptors such as SF1, PR, ERR-alpha1, and TR (PMID: 10894149), and is a putative tumor suppressor, playing a role in regulation of ribosomal RNA processing and thereby regulating cell proliferation (PMID: 30373810, PMID: 30455174). PNRC1 copy number loss and decreased gene expression has been identified in several tumor types (PMID: 30373810).
Additional content available in CKB BOOST