Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol DSTN
Synonyms ACTDP | ADF | bA462D18.2 | HEL32
Gene Description DSTN, destrin, actin depolymerizing factor, is a member of the ADF/cofilin protein family that regulates cytoskeletal dynamics and plays a role in cell growth, polarization, and migration (PMID: 18628996, PMID: 22898637, PMID: 32878967). Overexpression of Dstn has been observed in lung (PMID: 32878967) and pancreatic (PMID: 22898637) cancer, and a MET-DSTN fusion has been identified in lung adenocarcinoma (PMID: 34802880).
Additional content available in CKB BOOST