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Gene Detail

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Gene Symbol CIT
Synonyms CITK | CRIK | MCPH17 | STK21
Gene Description CIT, citron rho-interacting serine/threonine kinase, is an effector of Rho signaling (PMID: 27503289) and functions in cell division during cytokinesis (PMID: 29069760) and plays a role in the development of the nervous system (PMID: 27519304). Overexpression of Cit has been observed in colon cancer (PMID: 29069760) and a FGFR2 CIT fusion has been identified in lung adenocarcinoma (PMID: 23558953).
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