Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | WDHD1 | ||||||||||
| Synonyms | AND-1 | AND1 | CHTF4 | CTF4 | ||||||||||
| Gene Description | WDHD1, WD repeat and HMG-box DNA binding protein 1, encodes a cohesion establishment factor that plays a role in the assembly of replication complexes (PMID: 19805216, PMID: 20089864), recruitment of DNA helicases to the replication fork (PMID: 19661920, PMID: 27397686, PMID: 24255107), and in maintaining centromere integrity (PMID: 21266480). A fusion with FGFR2 and WDHD1 has been identified in cholangiocarcinoma (PMID: 33218975) and increased expression of WDHD1 has been identified in lung cancer and esophageal cancer (PMID: 20028748). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
