BAZ1A - Gene Detail
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| Gene Symbol | BAZ1A | ||||||||||||
| Synonyms | ACF1 | hACF1 | WALp1 | WCRF180 | ||||||||||||
| Gene Description | BAZ1A, bromodomain adjacent to zinc finger domain 1A, is the accessory subunit of an ATP-dependent chromatin remodeling complex involved in chromatin assembly (PMID: 10385622), nucleosome remodeling (PMID: 20033040), DNA replication (PMID: 12434153), senescence (PMID: 31085244), and DNA double-strand break repair (PMID: 21172662). BAZ1A mutations have been identified in gynaecologic carcinosarcomas (PMID: 25233892), and upregulation of Baz1a has been observed in various tumor types (PMID: 34736517), including colorectal cancer (PMID: 39112459), while BAZ1A deletion has been reported in papillary renal cell carcinoma (PMID: 22483639). | ||||||||||||
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