Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | MAP4K1 | ||||||||||
| Synonyms | HPK1 | ||||||||||
| Gene Description | MAP4K1, mitogen-activated protein kinase kinase kinase kinase 1, is a member of the MAPK4 family of serine/threonine kinases that plays a role in negative regulation of T-cell activation and proliferation, and regulates cell signaling pathways involved in cell growth, differentiation, and apoptosis (PMID: 31766293, PMID: 15770651). MAPK41 expression loss has been demonstrated in pancreatic ductal adenocarcinoma (PMID: 19141650). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
