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| Gene Symbol | CHN1 | ||||||||||
| Synonyms | ARHGAP2 | CHN | DURS2 | NC | RHOGAP2 | ||||||||||
| Gene Description | CHN1, chimerin 1, encodes a GTPase-activating protein that inactivates Rac1 (PMID: 21056981, PMID: 25676811), and plays a role in neuronal development, including regulation of ephrin signaling in neuronal motor circuit formation (PMID: 17785183, PMID: 17719550), development of ocular motor neurons (PMID: 18653847), and regulation of cortical neuronal migration (PMID: 22138645). Increased CHN1 expression has been identified in gastric cancer (PMID: 34152250). | ||||||||||
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