Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol PACSIN2
Synonyms SDPII
Gene Description PACSIN2, protein kinase C and casein kinase substrate in neurons 2, is a member of the F-BAR protein family that negatively regulates receptor-mediated endocytosis and growth factor mediated signaling, and plays a role in cell-cell adhesion (PMID: 23129763, PMID: 27417273, PMID: 11082044). A PACSIN2-BRAF fusion has been identified in pediatric langerhans cell histiocytosis (PMID: 28748614).
Additional content available in CKB BOOST