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Gene Detail

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Gene Symbol LEO1
Synonyms RDL
Gene Description LEO1, LEO1 homolog, Paf1/RNA polymerase II complex component, is a Paf1 complex component involved in transcription regulation (PMID: 20060942). A LEO1-SLC12A1 fusion has been identified in glioma (PMID: 20196086) and LEO1 gene dysregulation is thought to influence tumor development through Wnt signaling regulation (PMID: 17599057).
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