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CSF2RB - Gene Detail

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Gene Symbol CSF2RB
Synonyms betaGMR | CD131 | CDw131 | IL3RB | IL5RB | SMDP5
Gene Description CSF2RB, colony stimulating factor 2 receptor subunit beta, encodes the common beta chain of the IL-3, IL-5, and GM-CSF cytokine receptor complexes, which is required for signal transduction and plays a role in hematopoietic cell proliferation, differentiation, survival, and immune response (PMID: 17027509, PMID: 1833064, PMID: 23535386). Mutations in CSF2RB have been identified in breast cancer (PMID: 34729943) and leukemia (PMID: 27118405).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
1439 22 22q12.3 NM_000395 Unknown
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