CSNK2A1: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

CSNK2A1

Synonyms

CK2A1 | Cka1 | Cka2 | CKII | OCNDS

Gene Description

CSNK2A1, casein kinase 2 alpha 1, is the alpha catalytic subunit of the constitutively active CK2 protein kinase that interacts with acidic substrates and plays a role in cell growth and proliferation, apoptosis, autophagy (PMID: 31277672, PMID: 31500224, PMID: 12244125, PMID: 32626654), and may regulate mTORC1 activity (PMID: 32626654). Overexpression of CSNK2A1 has been identified in various tumors, including lymphoma, breast, kidney, and lung cancer (PMID: 25541719).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
1457	20	20p13	NM_001895	Unknown

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Gene Variants 6
Category Variants 1
Molecular Profiles 6
Evidence 5
Clinical Trials 0

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CSNK2A1 - Gene Detail

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