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CTNND1 - Gene Detail

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Gene Symbol CTNND1
Synonyms BCDS2 | CAS | CTNND | p120 | p120(CAS) | p120(CTN) | P120CAS | P120CTN
Gene Description CTNND1, catenin delta 1, encodes for p120-catenin, which plays a role in cell adhesion via association with E-cadherin, resulting in the regulation and stability of cadherins found at the cellular membrane (PMID: 23071139). CTNND1 amplification has been identified in lung cancer (PMID: 20715154), CTNND1 loss has been associated with breast cancer (PMID: 23733751), CTNND1 overexpression has been reported in hepatocellular carcinoma (PMID: 27193094), and a CTNND1 missense mutation has been observed in metastatic urothelial carcinoma (PMID: 31192134).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
1500 11 11q12.1 NM_001085458 Unknown
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