Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | DTX3L | ||||||||||
| Synonyms | BBAP | RNF143 | ||||||||||
| Gene Description | DTX3L, deltex E3 ubiquitin ligase 3L, is also known as B-lymphoma and BAL-associated protein (BBAP) and plays a role in histone modification and the DNA damage response through PARP1 activation (PMID: 23230272). DTX3L overexpression has been observed in melanoma (PMID: 26033450), in glioma patients with poor prognosis (PMID: 28627634), and may play a role in chemoresistance in hematological tumors (PMID: 28653881, PMID: 25605023). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
