Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | DLG1 | ||||||||||
| Synonyms | DLGH1 | hdlg | SAP-97 | SAP97 | ||||||||||
| Gene Description | DLG1, discs large MAGUK scaffold protein 1, encodes a scaffolding protein that plays a key role in cellular signaling and structure, including cellular polarity, cell to cell contact, and vesicle trafficking (PMID: 23829493). DLG1 mutations have been identified in mammary ductal carcinoma (PMID: 14871824), variable expression has been observed in colorectal cancer (PMID: 29263038), and endometrial cancer (PMID: 27002939), and a fusion with DLG1 and BRAF has been associated with colorectal cancer (PMID: 31911540). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
