Gene Detail
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| Gene Symbol | EDNRB | ||||||||||
| Synonyms | ABCDS | ET-B | ET-BR | ETB | ETB1 | ETBR | ETRB | HSCR | HSCR2 | WS4A | ||||||||||
| Gene Description | EDNRB, endothelin receptor type B, encodes for a G-protein coupled receptor that binds to endothelins, and plays a role in the development of the neural crest (PMID: 24326135). Elevated expression of EDNRB has been observed in esophageal squamous cell carcinoma (PMID: 24357795), breast cancer (PMID: 15073116), and vulvar cancer (PMID: 17611649). | ||||||||||
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