ARID2: Gene Detail - Cancer Knowledgebase (CKB)

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Gene Symbol

ARID2

Synonyms

BAF200 | CSS6 | p200 | SMARCF3 | ZIPZAP

Gene Description

ARID2, AT-rich interaction domain 2, is a member of the PBaF subunit (PMID: 32303701) of the SWI/SNF chromatin remodeling complex and is involved in cell-cycle activation (PMID: 29072391). Arid2 loss of function has been identified in hepatoceullar carcinoma (PMID: 22095441, PMID: 28238438), NSCLC (PMID: 23047306), papillary renal cell carcinoma (PMID: 25790038), oral squamous cell carcinoma (PMID: 29072391), urothelial carcinoma, and melanoma (PMID: 32303701).

NCBI Gene ID	Chromosome	Map Location	Canonical Transcript	Gene Role
196528	12	12q12	NM_152641	Tumor suppressor (PMID: 30606230)

Additional content available in

CKB BOOST

Gene Variants 39
Category Variants 6
Molecular Profiles 40
Evidence 6
Clinical Trials 4

KEY FEATURES

CKB CORE^TM

CKB BOOST^TM

CKB FLEX^TM

Access 50 genes & related content

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Genes

(50 Genes)

(2000+ Genes)

Gene Variants

Therapies

Limited

Global Drug Approvals

Drug Classes

Limited

Clinical Trials

Limited

Efficacy Evidence

Variant Tier Coding
(AMP/CAP/ASCO)

Advanced Search Capability

System Integration

More about our plans

The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2000 cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes while enabling a robust browse-like feature when the desired content is unknown.

Downloadable data from CKB is available using the FLEX version. CKB FLEX delivers CKB content as a flat file or JSON, enabling CKB data integration.

ARID2 - Gene Detail

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