Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene Symbol | ARID2 | ||||||||||
Synonyms | BAF200 | CSS6 | p200 | SMARCF3 | ZIPZAP | ||||||||||
Gene Description | ARID2, AT-rich interaction domain 2, is a member of the PBaF subunit (PMID: 32303701) of the SWI/SNF chromatin remodeling complex and is involved in cell-cycle activation (PMID: 29072391). Arid2 loss of function has been identified in hepatoceullar carcinoma (PMID: 22095441, PMID: 28238438), NSCLC (PMID: 23047306), papillary renal cell carcinoma (PMID: 25790038), oral squamous cell carcinoma (PMID: 29072391), urothelial carcinoma, and melanoma (PMID: 32303701). | ||||||||||
|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
ARID2 A205T | unknown | |
ARID2 - ALK | unknown | |
ARID2 - ALK EML4 - ALK | ||
ARID2 D1688H | unknown | |
ARID2 D248* | loss of function - predicted | |
ARID2 del | loss of function | |
ARID2 E1511K | unknown | |
ARID2 E1656K | unknown | |
ARID2 E267* | loss of function - predicted | |
ARID2 E75* | loss of function - predicted | |
ARID2 G1281A | unknown | |
ARID2 G1281W | unknown | |
ARID2 G1425S | unknown | |
ARID2 G1605fs | loss of function - predicted | |
ARID2 G590R | unknown | |
ARID2 H1017Y | unknown | |
ARID2 H1495fs | loss of function - predicted | |
ARID2 inact mut | loss of function | |
ARID2 K581* | loss of function - predicted | |
ARID2 L1423fs | loss of function - predicted | |
ARID2 L57* | loss of function - predicted | |
ARID2 M1346V | unknown | |
ARID2 mutant | unknown | |
ARID2 N67fs | loss of function - predicted | |
ARID2 P346L | unknown | |
ARID2 Q1016H | unknown | |
ARID2 Q819* | loss of function - predicted | |
ARID2 R1273* | loss of function | |
ARID2 R1769Q | unknown | |
ARID2 R314C | unknown | |
ARID2 R314S | unknown | |
ARID2 S1157* | loss of function - predicted | |
ARID2 S1327* | loss of function - predicted | |
ARID2 S218Pfs*74 | loss of function - predicted | |
ARID2 S297F | unknown | |
ARID2 S297P | unknown | |
ARID2 S319F | unknown | |
ARID2 S635* | loss of function - predicted | |
ARID2 W266* | loss of function - predicted | |
ARID2 wild-type | no effect |