Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol EIF4E
Synonyms AUTS19 | CBP | eIF-4E | EIF4E1 | EIF4EL1 | EIF4F
Gene Description EIF4E, eukaryotic translation initiation factor 4E, encodes a protein that is essential for initiation of protein translation in the cytoplasm and also plays a role in nuclear export of some mRNAs (PMID: 29396141, PMID: 20049173). EIF4E overexpression has been identified in multiple tumor types (PMID: 20049173) including breast (PMID: 7665244), head and neck (PMID: 9247311), and colorectal cancers (PMID: 28242042).
Additional content available in CKB BOOST