Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | EPHB6 | ||||||||||
| Synonyms | HEP | ||||||||||
| Gene Description | EPHB6, EPH receptor B6, is a kinase-inactive member of the erythropoietin-producing hepatocyte (Eph) receptor tyrosine kinase family that regulates cell adhesion and migration (PMID: 15955811, PMID: 31406248). Downregulation of EphB6 is associated with metastasis and invasive behavior in several tumor types (PMID: 25239188), including gastric cancer (PMID: 28453458) and colon cancer (PMID: 28262839), while overexpression has also been reported in colorectal cancer (PMID: 27145271) and pediatric T cell acute lymphoblastic leukemia (PMID: 29116180). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
