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ERBB4 - Gene Detail

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Gene Symbol ERBB4
Synonyms ALS19 | HER4 | p180erbB4
Gene Description ERBB4, erb-b2 receptor tyrosine kinase 4, encodes HER4, an ERBB family member that plays a role in cell survival and differentiation (PMID: 12648466). ERBB4 activating mutations are frequent in melanoma and have been demonstrated in lung adenocarcinoma (PMID: 19718025, PMID: 26050618).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
2066 2 2q34 NM_005235 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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