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Gene Symbol | ETS1 | ||||||||||
Synonyms | c-ets-1 | ETS-1 | EWSR2 | p54 | ||||||||||
Gene Description | ETS1, ETS proto-oncogene 1, transcription factor, encodes for an ETS family transcription factor involved in positive regulation of cytokines and chemokines (PMID: 20378371), promotion of angiogenic and extracellular matrix degradation, and is implicated in tumor invasiveness (PMID: 15574387, PMID: 22366814). ETS1 overexpression has been identified in several tumor types including breast (PMID: 12466970), ovarian (PMID: 11297247), and prostate cancer (PMID: 23064684). | ||||||||||
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