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ETV6 - Gene Detail

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Gene Symbol ETV6
Synonyms TEL | TEL/ABL | THC5
Gene Description ETV6, ets variant 6, is a member of the ETS family of transcription factors, which functions as a transcriptional repressor and is involved in hematopoietic differentiation (PMID: 16828711). Fusions of ETV6 with various partners are frequently associated with hematological cancers (PMID: 22578774) and ETV6 mutations have been identified in acute lymphoblastic leukemia (PMID: 22162831) and acute myeloid leukemia (PMID: 18305557).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
2120 12 12p13.2 NM_001987 Tumor suppressor (PMID: 30606230)
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