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EXT2 - Gene Detail

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Gene Symbol EXT2
Synonyms SOTV | SSMS
Gene Description EXT2, exostosin glycosyltransferase 2, is a transmembrane glycoprotein involved in heparan sulfate biosynthesis (PMID: 9756849, PMID: 11256613, PMID: 36402845). EXT2 mutations have been identified in chondrosarcoma (PMID: 15796962, PMID: 27636706) and increased Ext2 expression has been observed in head and neck squamous cell carcinoma (PMID: 38155009).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
2132 11 11p11.2 NM_207122 Unknown
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