EXT2 - Gene Detail
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| Gene Symbol | EXT2 | ||||||||||||
| Synonyms | SOTV | SSMS | ||||||||||||
| Gene Description | EXT2, exostosin glycosyltransferase 2, is a transmembrane glycoprotein involved in heparan sulfate biosynthesis (PMID: 9756849, PMID: 11256613, PMID: 36402845). EXT2 mutations have been identified in chondrosarcoma (PMID: 15796962, PMID: 27636706) and increased Ext2 expression has been observed in head and neck squamous cell carcinoma (PMID: 38155009). | ||||||||||||
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Additional content available in
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Comparison of CKB Offerings
KEY FEATURES
CKB BOOSTTM
Access 50 genes & related content
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Genes
(50 Genes)
(2000+ Genes)
Gene Variants
Therapies
Limited
Global Drug Approvals
Drug Classes
Limited
Clinical Trials
Limited
Efficacy Evidence
Variant Tier Coding
(AMP/CAP/ASCO)
(AMP/CAP/ASCO)
Advanced Search Capability
System Integration
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The public access version, CKB CORE™, encompasses 50 cancer-related genes, and every quarter, a
select group of genes are exchanged, focusing on a specific theme. Users can search CKB CORE™ via
gene and gene variants. The web-based, subscription version, CKB BOOST™, includes more than 2000
cancer-related genes and is designed to interrogate the knowledgebase for specific data attributes
while enabling a robust browse-like feature when the desired content is unknown.
Downloadable data from CKB is available using the FLEX version. CKB FLEX delivers CKB content as a
flat file or JSON, enabling CKB data integration.
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CKB BOOST
for more information.
Contact: ckbsupport@genomenon.com