Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene Symbol | ALCAM | ||||||||||
| Synonyms | CD166 | MEMD | ||||||||||
| Gene Description | ALCAM, activated leukocyte cell adhesion molecule, is a transmembrane glycoprotein and a member of the immunoglobulin superfamily that facilitates cell clustering via homophilic and heterophilic interactions, and thereby plays a role in cell growth, migration, differentiation, and hematopoiesis (PMID: 12113472, PMID: 30778704). Increased expression of ALCAM has been identified in several solid tumors, including esophageal, prostate, and bladder carcinomas, pancreatic cancer (PMID: 20952758), melanoma (PMID: 10702391), oral squamous cell carcinoma (PMID: 19142865), and esophageal squamous cell carcinoma (PMID: 16024937), and reduced expression has been identified in breast cancer (PMID: 15318930). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
