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Gene Symbol FANCF
Synonyms FAF
Gene Description FANCF, FA complementation group F, is a member of the Fanconi anemia core complex, which plays a role in DNA damage response (PMID: 24910428) through homologous recombination DNA repair (PMID: 30822218). FANCF mutations are associated with Fanconi anemia, and aberrant FANCF promoter methylation has been demonstrated in ovarian cancer (PMID: 26507869, PMID: 16675878).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
2188 11 11p14.3 NM_022725 Tumor suppressor (PMID: 30606230)
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