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Gene Symbol FES
Synonyms FPS
Gene Description FES, FES proto-oncogene, tyrosine kinase, plays a role in the maintenance of cellular transformation and demonstrates both oncogenic and tumor suppressive roles in cancer (PMID: 22202072). Decreased expression of Fes in melanoma has been commonly observed (PMID: 28463229) and inhibition of Fes may promote radiosensitivity (PMID: 31573955).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
2242 15 15q26.1 NM_002005 Both: Oncogene and Tumor suppressor (PMID: 30606230)
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