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Gene Symbol FGF7
Synonyms HBGF-7 | KGF
Gene Description FGF7, fibroblast growth factor 7, also known as keratinocyte growth factor, binds FGFR2 (PMID: 16597617) to activate MAPK and PIK3 signaling pathways to regulate cell proliferation, migration, and differentiation (PMID: 28339036). Overexpression of Fgf7 has been observed in bladder urothelial carcinoma (PMID: 25623741), gastric cancer (PMID: 17049492), and prostatic hyperplasia (PMID: 10411093).
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