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| Gene Symbol | RRAS2 | ||||||||||
| Synonyms | NS12 | TC21 | ||||||||||
| Gene Description | RRAS2, RAS related 2, encodes a member of the RAS family of GTPases, which acts as a regulator of several signal transduction pathways including the PI3K/Akt pathway (PMID: 11850823) and the MAPK/ERK pathway (PMID: 17656362, PMID: 10064593), thereby playing a role in cell survival, proliferation, and transformation (PMID: 11850823, PMID: 17656362, PMID: 10064593). RRAS2 overexpression has been identified in tumors of the central nervous system (PMID: 24148564). | ||||||||||
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