Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene Symbol | KDM4B | ||||||||||
Synonyms | JMJD2B | MRD65 | TDRD14B | ||||||||||
Gene Description | KDM4B, lysine demethylase 4B, is a Jumonji domain histone demethylase and epigenetic modulator that regulates gene transcription through chromatin remodeling to influence cell growth and differentiation (PMID: 24349617, PMID: 30759871). Overexpression of Kdm4b has been observed in prostate cancer (PMID: 31468537), ER-positive breast cancer (PMID: 24349617), colorectal cancer (PMID: 30759871), and gastric cancer (PMID: 30683841). | ||||||||||
|