Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol FOXO1
Synonyms FKH1 | FKHR | FOXO1A
Gene Description FOXO1, forkhead box O1, encodes for a protein belonging to the family of forkhead box O transcription factors, which plays a role in multiple cellular processes including cell cycle arrest, apoptosis, and prevention of reactive oxygen species (PMID: 18715783). FOXO1 fusions are frequently observed in alveolar rhabdomyosarcoma (PMID: 24334454), including FOXO1-FGFR1 (PMID: 21666686), PAX3-FOXO1 (PMID: 24334454), and PAX7-FOXO1 (PMID: 12865925, PMID: 8187070).
Additional content available in CKB BOOST