Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene Symbol ARHGAP26
Synonyms GRAF | GRAF1 | OPHN1L | OPHN1L1
Gene Description ARHGAP26, Rho GTPase activating protein 26, encodes for a protein that negatively regulates the Rho family by converting RhoA and Cdc42 to their inactive forms via GDP binding, and is necessary for muscle development (PMID: 24067935). A CLDN18-ARHGAP26 fusion has been identified in gastric cancer, primarily including those of the diffuse-type (PMID: 30034621).
Additional content available in CKB BOOST